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The Use of Intravitreal Ranibizumab for Choroidal Neovascularization Associated with Vogt-Koyanagi-Harada Syndrome
Joint Authors
Kolomeyer, Anton M.
Roy, Monique S.
Chu, David S.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-03
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Purpose.
To describe the use of intravitreal ranibizumab for choroidal neovascular membrane (CNVM) secondary to Vogt-Koyanagi-Harada (VKH) syndrome.
Methods.
Interventional case report.
Results.
A 50-year-old woman presented with conjunctival injection and bilateral eye pain.
Vision was 20/400 and 20/80 in the right and left eyes, respectively.
Bilateral iritis, vitritis, and choroidal thickening were evident.
Exudative retinal detachment was present in the left eye.
Corticosteroid treatment improved vision to 20/40 bilaterally.
Methotrexate (MTX) was initiated and vision remained stable for 3 months.
After a 5-month loss to follow-up, vision in the left eye decreased to finger counting (CF) and a parafoveal CNVM was identified.
After 3 intravitreal ranibizumab injections, vision improved to 20/40.
Twelve months later, despite inflammation control, vision decrease to CF due to recurrent CNVM.
A fourth ranibizumab injection was given.
Twenty months later, best-corrected vision was 20/400, and an inactive CNVM was present in the left eye.
Conclusion.
After initial CNVM regression and visual acuity improvement due to ranibizumab, the CNVM recurred and became refractory to treatment.
Despite control of inflammation and neovascularization, VKH chronicity lead to permanent vision loss in our patient.
A combinational treatment approach may be required in such patients.
American Psychological Association (APA)
Kolomeyer, Anton M.& Roy, Monique S.& Chu, David S.. 2011. The Use of Intravitreal Ranibizumab for Choroidal Neovascularization Associated with Vogt-Koyanagi-Harada Syndrome. Case Reports in Medicine،Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-495512
Modern Language Association (MLA)
Kolomeyer, Anton M.…[et al.]. The Use of Intravitreal Ranibizumab for Choroidal Neovascularization Associated with Vogt-Koyanagi-Harada Syndrome. Case Reports in Medicine No. 2011 (2011), pp.1-3.
https://search.emarefa.net/detail/BIM-495512
American Medical Association (AMA)
Kolomeyer, Anton M.& Roy, Monique S.& Chu, David S.. The Use of Intravitreal Ranibizumab for Choroidal Neovascularization Associated with Vogt-Koyanagi-Harada Syndrome. Case Reports in Medicine. 2011. Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-495512
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495512