The Role of Adipokines in Understanding the Associations between Obesity and Depression
Joint Authors
MacQueen, Glenda M.
Taylor, Valerie H.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-07-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
Two major causes of disability, major depression and obesity, share overlapping psychosocial and pathophysiological etiologies.
Studies are now focused on biological mechanisms linking the two illnesses, and there is interest in the role that adipokines may have in mediating the association between obesity and depression.
We reviewed the literature to look at what is currently known about this association, focusing on the adipokines leptin, adiponectin, and resistin.
Methods.
A MEDLINE search, citing articles from 1966 onward, supplemented by a review of bibliographies, was conducted to identify relevant studies.
Results.
This paper identified plausible pathways underlying a link between adipokines and depression.
Only a few studies have yet been conducted specifically examining these biomarkers in patients with depression, but the results are intriguing.
Conclusion.
This paper is one of the first to examine the association between adipokines and depression.
It provides an overview of the physiological role of adipokines and summarizes the data suggesting that they may be dysregulated in major depression.
This area of research may become increasingly important as new treatment strategies are developed.
American Psychological Association (APA)
Taylor, Valerie H.& MacQueen, Glenda M.. 2010. The Role of Adipokines in Understanding the Associations between Obesity and Depression. Journal of Obesity،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-495533
Modern Language Association (MLA)
Taylor, Valerie H.& MacQueen, Glenda M.. The Role of Adipokines in Understanding the Associations between Obesity and Depression. Journal of Obesity No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-495533
American Medical Association (AMA)
Taylor, Valerie H.& MacQueen, Glenda M.. The Role of Adipokines in Understanding the Associations between Obesity and Depression. Journal of Obesity. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-495533
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495533