Propolis Modulates Fibronectin Expression in the Matrix of Thermal Injury
Joint Authors
Kozma, Ewa M.
Stojko, Jerzy
Olczyk, Pawel
Wisowski, Grzegorz
Mencner, Łukasz
Komosinska-Vassev, Katarzyna
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-11
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The aim of the study was to assess the propolis effect on fibronectin metabolism in the course of burn wounds healing process.
A model of burn wound healing of pig skin was applied.
The amount of the released glycoprotein was assessed by a surface plasmon resonance.
The profile of extracted fibronectin components was also assessed by an electrophoresis in polyacrylamide gel, with a subsequent immunodetection by Western Blotting.
Propolis burn treatment decreased the release of fibronectin components from healing wounds in relation to damages treated with silver sulfadiazine.
The main reason of decreased extraction of fibronectin components from wounds treated with propolis was a substantial decrease of degradation product release of the mentioned glycoprotein, which was observed particularly from the 3rd to 5th day of the repair.
Wounds treatment with propolis demonstrated, especially in relation to damages treated with silver sulfadiazine, the decreased release of synthesized fibronectin molecules.
The obtained results suggest that propolis modifies fibronectin metabolism in the course of wound healing process.
The influence of propolis is reflected in prevention of fibronectin biosynthesis as well as its degradation in the wound area.
The above-mentioned metabolic changes may decrease the risk of complications in the repair wounds process.
American Psychological Association (APA)
Olczyk, Pawel& Komosinska-Vassev, Katarzyna& Wisowski, Grzegorz& Mencner, Łukasz& Stojko, Jerzy& Kozma, Ewa M.. 2014. Propolis Modulates Fibronectin Expression in the Matrix of Thermal Injury. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-495540
Modern Language Association (MLA)
Olczyk, Pawel…[et al.]. Propolis Modulates Fibronectin Expression in the Matrix of Thermal Injury. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-495540
American Medical Association (AMA)
Olczyk, Pawel& Komosinska-Vassev, Katarzyna& Wisowski, Grzegorz& Mencner, Łukasz& Stojko, Jerzy& Kozma, Ewa M.. Propolis Modulates Fibronectin Expression in the Matrix of Thermal Injury. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-495540
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495540