Merkel Cell Carcinoma : A Retrospective Study on 48 Cases and Review of Literature
Joint Authors
Martinotti, Mario
Cafaro, Ines
Cirillo, Fernando
Vismarra, Marco
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine tumor of the skin.
Fourty-eight patients with MCC were observed at the Rare Hormonal Tumors Group of Cremona Hospital, 15 of these with unknown primary site.
Due to rarity of Merkel cell carcinoma, clinical experience is generally limited.
Data from our series confirm the current recommendations.
Wide surgical excision must be associated with radiotherapy also in early stages in order to avoid local relapse and the rapid progression of disease.
In advanced stages chemotherapy is the standard despite the short duration of responses and poor quality of life.
The data of our series, characterized by a high demand for second opinion, offer some insight about the real rarity of the tumor, the difficulty of managing of disease in our country secondary to a wrong cultural approach to the problem, the indiscriminate use of molecules unnecessary and often expensive, the lack of protocols, and the presence of guidelines often ignored.
This results in very poor survival associated with a very low quality of life, requiring to find the right direction towards a correct management of disease.
American Psychological Association (APA)
Cirillo, Fernando& Vismarra, Marco& Cafaro, Ines& Martinotti, Mario. 2012. Merkel Cell Carcinoma : A Retrospective Study on 48 Cases and Review of Literature. Journal of Oncology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-495632
Modern Language Association (MLA)
Cirillo, Fernando…[et al.]. Merkel Cell Carcinoma : A Retrospective Study on 48 Cases and Review of Literature. Journal of Oncology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-495632
American Medical Association (AMA)
Cirillo, Fernando& Vismarra, Marco& Cafaro, Ines& Martinotti, Mario. Merkel Cell Carcinoma : A Retrospective Study on 48 Cases and Review of Literature. Journal of Oncology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-495632
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495632