Omega-3 Fatty Acid Enriched Chevon (Goat Meat) Lowers Plasma Cholesterol Levels and Alters Gene Expressions in Rats
Joint Authors
Soleimani Farjam, Abdoreza
Ebrahimi, Mahdi
Rajion, Mohamed Ali
Meng, Goh Yong
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
In this study, control chevon (goat meat) and omega-3 fatty acid enriched chevon were obtained from goats fed a 50% oil palm frond diet and commercial goat concentrate for 100 days, respectively.
Goats fed the 50% oil palm frond diet contained high amounts of α-linolenic acid (ALA) in their meat compared to goats fed the control diet.
The chevon was then used to prepare two types of pellets (control or enriched chevon) that were then fed to twenty-male-four-month-old Sprague-Dawley rats (n=10 in each group) for 12 weeks to evaluate their effects on plasma cholesterol levels, tissue fatty acids, and gene expression.
There was a significant increase in ALA and docosahexaenoic acid (DHA) in the muscle tissues and liver of the rats fed the enriched chevon compared with the control group.
Plasma cholesterol also decreased (P<0.05) in rats fed the enriched chevon compared to the control group.
The rat pellets containing enriched chevon significantly upregulated the key transcription factor PPAR-γ and downregulated SREBP-1c expression relative to the control group.
The results showed that the omega-3 fatty acid enriched chevon increased the omega-3 fatty acids in the rat tissues and altered PPAR-γ and SREBP-1c genes expression.
American Psychological Association (APA)
Ebrahimi, Mahdi& Rajion, Mohamed Ali& Meng, Goh Yong& Soleimani Farjam, Abdoreza. 2014. Omega-3 Fatty Acid Enriched Chevon (Goat Meat) Lowers Plasma Cholesterol Levels and Alters Gene Expressions in Rats. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-495667
Modern Language Association (MLA)
Ebrahimi, Mahdi…[et al.]. Omega-3 Fatty Acid Enriched Chevon (Goat Meat) Lowers Plasma Cholesterol Levels and Alters Gene Expressions in Rats. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-495667
American Medical Association (AMA)
Ebrahimi, Mahdi& Rajion, Mohamed Ali& Meng, Goh Yong& Soleimani Farjam, Abdoreza. Omega-3 Fatty Acid Enriched Chevon (Goat Meat) Lowers Plasma Cholesterol Levels and Alters Gene Expressions in Rats. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-495667
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495667