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Long-Term Follow-Up of a Child with Autoimmune Thyroiditis and Recurrent Hyperthyroidism in the Absence of TSH Receptor Antibodies
Joint Authors
Dunne, Christopher
De Luca, Francesco
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Hashitoxicosis is an initial, transient, hyperthyroid phase that rarely affects patients with Hashimoto thyroiditis.
We present here an unusual case of a child with Hashimoto thyroiditis and recurrent hyperthyroidism.
A 4 yr 6/12 old male was diagnosed by us with autoimmune subclinical hypothyroidism (normal free T4, slightly elevated TSH, and elevated TG antibody titer).
Two years and 6/12 later he experienced increased appetite and poor weight gain; a laboratory evaluation revealed suppressed TSH, elevated free T4, and normal TSI titer.
In addition, an I123 thyroid uptake was borderline-low.
A month later, the free T4 had normalized.
After remaining asymptomatic for 3 years, the patient presented again with increased appetite, and he was found with low TSH and high free T4.
Within the following 3 months, his free T4 and TSH normalized.
At his most recent evaluation, his TSH was normal and the free T4 was borderline-high; the TG antibody titer was still elevated and the TSI titer was negative.
To our knowledge, this is the first patient reported with Hashimoto thyroiditis and recurrent hyperthyroidism.
This case exemplifies the variability of the manifestations and natural history of Hashimoto thyroiditis and supports the need for a long-term evaluation of patients with autoimmune thyroid disease.
American Psychological Association (APA)
Dunne, Christopher& De Luca, Francesco. 2014. Long-Term Follow-Up of a Child with Autoimmune Thyroiditis and Recurrent Hyperthyroidism in the Absence of TSH Receptor Antibodies. Case Reports in Endocrinology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-495691
Modern Language Association (MLA)
Dunne, Christopher& De Luca, Francesco. Long-Term Follow-Up of a Child with Autoimmune Thyroiditis and Recurrent Hyperthyroidism in the Absence of TSH Receptor Antibodies. Case Reports in Endocrinology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-495691
American Medical Association (AMA)
Dunne, Christopher& De Luca, Francesco. Long-Term Follow-Up of a Child with Autoimmune Thyroiditis and Recurrent Hyperthyroidism in the Absence of TSH Receptor Antibodies. Case Reports in Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-495691
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495691