Endogenous and Exogenous CD1-Binding Glycolipids
Joint Authors
Cheng, Janice M. H.
Stocker, Bridget L.
Timmer, Mattie S. M.
Khan, Ashna A.
Source
International Journal of Carbohydrate Chemistry
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-05
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
In the same way that peptide antigens are presented by major histocompatibility complex (MHC) molecules, glycolipid antigens can also activate the immune response via binding to CD1 proteins on antigen-presenting cells (APCs) and stimulate CD1-restricted T cells.
In humans, there are five members of the CD1 family, termed CD1a–e, of which CD1a–d are involved in glycolipid presentation at the cell surface, while CD1e is involved in the intracellular trafficking of glycolipid antigens.
Both endogenous (self-derived) and exogenous (non-self-derived) glycolipids have been shown to bind to members of the CD1 family with varying degrees of specificity.
In this paper we focus on the key glycolipids that bind to the different members of the CD1 family.
American Psychological Association (APA)
Cheng, Janice M. H.& Khan, Ashna A.& Timmer, Mattie S. M.& Stocker, Bridget L.. 2011. Endogenous and Exogenous CD1-Binding Glycolipids. International Journal of Carbohydrate Chemistry،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-495694
Modern Language Association (MLA)
Cheng, Janice M. H.…[et al.]. Endogenous and Exogenous CD1-Binding Glycolipids. International Journal of Carbohydrate Chemistry No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-495694
American Medical Association (AMA)
Cheng, Janice M. H.& Khan, Ashna A.& Timmer, Mattie S. M.& Stocker, Bridget L.. Endogenous and Exogenous CD1-Binding Glycolipids. International Journal of Carbohydrate Chemistry. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-495694
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495694