An Increase of the Character Function of Self-Directedness Is Centrally Involved in Symptom Reduction during Remission from Major Depression
Joint Authors
Goekoop, Rutger
Goekoop, Jaap G.
De Winter, Remco F. P.
Source
Depression Research and Treatment
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Studies with the Temperament and Character Inventory (TCI) in depressive disorders have shown changes (Δ) of the character of Self-Directedness (SD) and the temperament of Harm Avoidance (HA).
The central question of this study is which of these two changes is most proximally related to the production of depressive symptoms.
Methods.
The start and endpoint data from a two-year followup of 58 depressed patients were reanalyzed.
We used the ΔHA and ΔSD scores as well as the Δ scores on three dimensions of psychopathology, called Emotional Dysregulation (ED), Retardation (RET), and Anxiety (ANX).
The presence of the main relation between personality and psychopathology was tested in all patients and in four subcategories.
The data were analyzed by MANCOVA and Structural Equation Modelling (SEM).
Results.
ΔHA and ΔSD correlated negatively, and only ΔSD was related (negatively) to ΔED.
This pattern was found in all subcategories.
SEM showed ΔHA and ΔSD had an ambiguous causal interrelationship, while ΔSD, ΔRET, and ΔANX had unidirectional effects on ΔED.
Conclusion.
The results correspond with a central pathogenetic role for a state-related deficit at the character level in depression.
This may have important consequences for investigations of endophenotypes and clinical treatment.
American Psychological Association (APA)
Goekoop, Jaap G.& De Winter, Remco F. P.& Goekoop, Rutger. 2011. An Increase of the Character Function of Self-Directedness Is Centrally Involved in Symptom Reduction during Remission from Major Depression. Depression Research and Treatment،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-495699
Modern Language Association (MLA)
Goekoop, Jaap G.…[et al.]. An Increase of the Character Function of Self-Directedness Is Centrally Involved in Symptom Reduction during Remission from Major Depression. Depression Research and Treatment No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-495699
American Medical Association (AMA)
Goekoop, Jaap G.& De Winter, Remco F. P.& Goekoop, Rutger. An Increase of the Character Function of Self-Directedness Is Centrally Involved in Symptom Reduction during Remission from Major Depression. Depression Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-495699
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495699