Endoscopic Resection and Topical 5-Fluorouracil as an Alternative Treatment to Craniofacial Resection for the Management of Primary Intestinal-Type Sinonasal Adenocarcinoma
Joint Authors
Khalil, Hisham
Mackie, Simon
Malik, Tass
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
Intestinal-type adenocarcinoma of the sinonasal tract is very rare and is responsible for less than 4% of tumours of the sinuses.
Craniofacial resection has been the mainstay of treatment for many years; however, techniques for endoscopic resection are constantly being developed.
Discussion.
The use of transnasal endoscopic resection (TER) and topical chemotherapy applications as an alternative to cranio-facial resection (CFR) is discussed.
TER offers advantages over CFR in terms of fewer intra-operative complications and an improved cosmetic outcome.
Survival and metastatic rates are similar between both procedures.
Patients with locally invasive tumours are better managed with CFR.
Topical applications of 5-Fluorouracil has been shown to be effective in increasing survival in patients with sino-nasal malignancy.
Conclusion.
Trans-nasal endoscopic resection and topical 5-Fluorouracil could potentially offer an acceptable alternative treatment to the standard of cranio-facial resection.
This should be investigated in trials with a longer followup period than this paper in order to directly compare the two treatment modalities.
American Psychological Association (APA)
Mackie, Simon& Malik, Tass& Khalil, Hisham. 2011. Endoscopic Resection and Topical 5-Fluorouracil as an Alternative Treatment to Craniofacial Resection for the Management of Primary Intestinal-Type Sinonasal Adenocarcinoma. Minimally Invasive Surgery،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-495748
Modern Language Association (MLA)
Mackie, Simon…[et al.]. Endoscopic Resection and Topical 5-Fluorouracil as an Alternative Treatment to Craniofacial Resection for the Management of Primary Intestinal-Type Sinonasal Adenocarcinoma. Minimally Invasive Surgery No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-495748
American Medical Association (AMA)
Mackie, Simon& Malik, Tass& Khalil, Hisham. Endoscopic Resection and Topical 5-Fluorouracil as an Alternative Treatment to Craniofacial Resection for the Management of Primary Intestinal-Type Sinonasal Adenocarcinoma. Minimally Invasive Surgery. 2011. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-495748
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495748