![](/images/graphics-bg.png)
Inflammation, Diabetes, and Chronic Kidney Disease : Role of Aerobic Capacity
Joint Authors
Gonçalves, Renato de Souza
Barreti, Pasqual
Oliveira e Silva, Viviana Rugolo
Hueb, João Carlos
Franco, Roberto Jorge da Silva
Caramori, Jacqueline Costa Teixeira
Stringuetta Belik, Fernanda
Martin, Luis Cuadrado
Shiraishi, Flávio Gobbis
Source
Experimental Diabetes Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The persistent inflammatory state is common in diabetes and chronic kidney disease (CKD).
These patients present exercise intolerance and increased arterial stiffness.
Long-term aerobic exercise has been associated with better arterial compliance, antidiabetic and antiinflammatory benefits.
We assessed the hypothesis that in patients with diabetes and CKD, better aerobic capacity is associated with less inflammatory state and arterial stiffness.
Thirty-nine CKD patients (17 in hemodialysis) were evaluated.
According to CKD etiology two patient groups were obtained: group of diabetics (GD) was formed by 11 patients and nondiabetics (GND) formed by 28 patients.
Central blood pressure and arterial stiffness were evaluated by Sphygmocor device.
Carotida intima-media thickness (CA-IMT) was evaluated by ultrasonography.
Aerobic capacity was measured by estimated VO2max according to treadmill test by Bruce protocol.
The GD showed a higher frequency of C-reactive protein above laboratory cutoff (P=0.044), higher frequency of male gender, and a non significant higher value of VO2max (P=0.099).
The CA-IMT was similar.
Only better aerobic capacity was associated with lower frequency of high C-reactive protein when adjusted to diabetes and gender in a logistic regression model.
In conclusion, aerobic capacity was associated with inflammatory state, in CKD patients, independently of diabetes presence.
American Psychological Association (APA)
Shiraishi, Flávio Gobbis& Stringuetta Belik, Fernanda& Oliveira e Silva, Viviana Rugolo& Martin, Luis Cuadrado& Hueb, João Carlos& Gonçalves, Renato de Souza…[et al.]. 2012. Inflammation, Diabetes, and Chronic Kidney Disease : Role of Aerobic Capacity. Experimental Diabetes Research،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-495753
Modern Language Association (MLA)
Shiraishi, Flávio Gobbis…[et al.]. Inflammation, Diabetes, and Chronic Kidney Disease : Role of Aerobic Capacity. Experimental Diabetes Research No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-495753
American Medical Association (AMA)
Shiraishi, Flávio Gobbis& Stringuetta Belik, Fernanda& Oliveira e Silva, Viviana Rugolo& Martin, Luis Cuadrado& Hueb, João Carlos& Gonçalves, Renato de Souza…[et al.]. Inflammation, Diabetes, and Chronic Kidney Disease : Role of Aerobic Capacity. Experimental Diabetes Research. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-495753
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495753