Repetitive Transcranial Magnetic Stimulation Improves Handwriting in Parkinson’s Disease
Joint Authors
Boyd, Lara A.
Farley, Becky G.
Randhawa, Bubblepreet K.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Parkinson disease (PD) is characterized by hypometric movements resulting from loss of dopaminergic neurons in the substantia nigra.
PD leads to decreased activation of the supplementary motor area (SMA); the net result of these changes is a poverty of movement.
The present study determined the impact of 5 Hz repetitive transcranial magnetic stimulation (rTMS) over the SMA on a fine motor movement, handwriting (writing cursive “l”s), and on cortical excitability, in individuals with PD.
Methods.
In a cross-over design, ten individuals with PD were randomized to receive either 5 Hz or control stimulation over the SMA.
Immediately following brain stimulation right handed writing was assessed.
Results.
5 Hz stimulation increased vertical size of handwriting and diminished axial pressure.
In addition, 5 Hz rTMS significantly decreased the threshold for excitability in the primary motor cortex.
Conclusions.
These data suggest that in the short term 5 Hz rTMS benefits functional fine motor task performance, perhaps by altering cortical excitability across a network of brain regions.
Further, these data may provide the foundation for a larger investigation of the effects of noninvasive brain stimulation over the SMA in individuals with PD.
American Psychological Association (APA)
Randhawa, Bubblepreet K.& Farley, Becky G.& Boyd, Lara A.. 2013. Repetitive Transcranial Magnetic Stimulation Improves Handwriting in Parkinson’s Disease. Parkinson’s Disease،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-495902
Modern Language Association (MLA)
Randhawa, Bubblepreet K.…[et al.]. Repetitive Transcranial Magnetic Stimulation Improves Handwriting in Parkinson’s Disease. Parkinson’s Disease No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-495902
American Medical Association (AMA)
Randhawa, Bubblepreet K.& Farley, Becky G.& Boyd, Lara A.. Repetitive Transcranial Magnetic Stimulation Improves Handwriting in Parkinson’s Disease. Parkinson’s Disease. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-495902
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495902