Current Concepts in the Treatment of Retinitis Pigmentosa
Joint Authors
MacDonald, Ian M.
Musarella, Maria A.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Inherited retinal degenerations, including retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA), affect 1 in 4000 individuals in the general population.
A majority of the genes which are mutated in these conditions are expressed in either photoreceptors or the retinal pigment epithelium (RPE).
There is considerable variation in the clinical severity of these conditions; the most severe being autosomal recessive LCA, a heterogeneous retinal degenerative disease and the commonest cause of congenital blindness in children.
Here, we discuss all the potential treatments that are now available for retinal degeneration.
A number of therapeutic avenues are being explored based on our knowledge of the pathophysiology of retinal degeneration derived from research on animal models, including: gene therapy, antiapoptosis agents, neurotrophic factors, and dietary supplementation.
Technological advances in retinal implant devices continue to provide the promise of vision for patients with end-stage disease.
American Psychological Association (APA)
Musarella, Maria A.& MacDonald, Ian M.. 2010. Current Concepts in the Treatment of Retinitis Pigmentosa. Journal of Ophthalmology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-496059
Modern Language Association (MLA)
Musarella, Maria A.& MacDonald, Ian M.. Current Concepts in the Treatment of Retinitis Pigmentosa. Journal of Ophthalmology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-496059
American Medical Association (AMA)
Musarella, Maria A.& MacDonald, Ian M.. Current Concepts in the Treatment of Retinitis Pigmentosa. Journal of Ophthalmology. 2010. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-496059
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496059