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Comparison of Fine Needle Aspiration Cytology and Thyroid Scan in Solitary Thyroid Nodule
Joint Authors
Basharat, Rabia
Hamid, Tahira
Saeed, Shahzad
Bukhari, Mulazim Hussain
Source
Pathology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-04
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
This was a comparative study between FNAC and thyroid scan used to diagnose the solitary thyroid nodule and histopathology was used as gold standard to compare the results of both modalities.
We hypothesized that Fine needle aspiration cytology and thyroid scan diagnose solitary thyroid nodule (STN) as accurately as histopathology.
Materials and Methods.
This study comprised of 50 patients with solitary thyroid nodules (STN) presented to OPD.
After clinical examination these patients were referred to Centre for Nuclear Medicine, Mayo Hospital Lahore for thyroid function tests and thyroid scan (TS).
These patients underwent FNAC in the department of Pathology and surgery in Mayo Hospital.
The cases were operated and evaluated for histopathological changes.
Results.
On thyroid scan, 40 patients (80%) having cold nodule were labeled as suspicious 10 patients (20%) had hot nodule.
On FNAC 23 patients (46%) had benign lesion, 22 patients (44%) had indeterminate lesion and 5 patients (10%) had malignant lesions.
On histopathology, 45 patients (90%) were confirmed to have benign lesions and 5 patients (10%), malignant lesions.
After comparison of results of thyroid scan and FNAC with histopathology, the sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of thyroid scan were 80%, 20%, 10%, 90% and 26%, respectively whereas those of FNAC were 80%, 97.7%, 80%, 97.7% and 96%, respectively.
Conclusion.
Fine needle aspiration was a significantly better predictor of malignancy than thyroid scan and resulted in a smaller proportion of excisions for benign nodules.
American Psychological Association (APA)
Basharat, Rabia& Bukhari, Mulazim Hussain& Saeed, Shahzad& Hamid, Tahira. 2011. Comparison of Fine Needle Aspiration Cytology and Thyroid Scan in Solitary Thyroid Nodule. Pathology Research International،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-496111
Modern Language Association (MLA)
Basharat, Rabia…[et al.]. Comparison of Fine Needle Aspiration Cytology and Thyroid Scan in Solitary Thyroid Nodule. Pathology Research International No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-496111
American Medical Association (AMA)
Basharat, Rabia& Bukhari, Mulazim Hussain& Saeed, Shahzad& Hamid, Tahira. Comparison of Fine Needle Aspiration Cytology and Thyroid Scan in Solitary Thyroid Nodule. Pathology Research International. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-496111
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496111