Corneal Collagen Cross-Linking with Hypoosmolar Riboflavin Solution in Keratoconic Corneas
Joint Authors
Mu, Guoying
Fan, Zhaoshan
Wang, Lihua
Gu, Shaofeng
Tao, Xiangchen
Zhang, Yong
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-14
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To report the 12-month outcomes of corneal collagen cross-linking (CXL) with a hypoosmolar riboflavin and ultraviolet-A (UVA) irradiation in thin corneas.
Methods.
Eight eyes underwent CXL using a hypoosmolar riboflavin solution after epithelial removal.
The corrected distance visual acuity (CDVA), manifest refraction, the mean thinnest corneal thickness (MTCT), and the endothelial cell density (ECD) were evaluated before and 6 and 12 months after CXL.
Results.
The MTCT was 413.9 ± 12.4 μm before treatment and reduced to 381.1 ± 7.3 μm after the removal of the epithelium.
After CXL, the thickness decreased to 410.3 ± 14.5 μm at the last follow-up.
Before treatment, the mean K-value of the apex of the keratoconus corneas was 58.7 ± 3.5 diopters and slightly decreased (57.7 ± 4.9 diopters) at 12 months.
The mean CDVA was 0.54 ± 0.23 logarithm of the minimal angle of resolution before treatment and increased to 0.51 ± 0.21 logarithm at the last follow-up.
The ECD was 2731.4 ± 191.8 cells/mm2 before treatment and was 2733.4 ± 222.6 cells/mm2 at 12 months after treatment.
Conclusions.
CXL with a hypoosmolar riboflavin in thin corneas seems to be a promising method for keratoconic eyes with the mean thinnest corneal thickness less than 400 μm without epithelium.
American Psychological Association (APA)
Gu, Shaofeng& Fan, Zhaoshan& Wang, Lihua& Tao, Xiangchen& Zhang, Yong& Mu, Guoying. 2014. Corneal Collagen Cross-Linking with Hypoosmolar Riboflavin Solution in Keratoconic Corneas. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-496127
Modern Language Association (MLA)
Gu, Shaofeng…[et al.]. Corneal Collagen Cross-Linking with Hypoosmolar Riboflavin Solution in Keratoconic Corneas. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-496127
American Medical Association (AMA)
Gu, Shaofeng& Fan, Zhaoshan& Wang, Lihua& Tao, Xiangchen& Zhang, Yong& Mu, Guoying. Corneal Collagen Cross-Linking with Hypoosmolar Riboflavin Solution in Keratoconic Corneas. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-496127
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496127