Electroacupuncture at ST36-ST37 and at Ear Ameliorates Hippocampal Mossy Fiber Sprouting in Kainic Acid-Induced Epileptic Seizure Rats

Joint Authors

Hsu, Hsin-Cheng
Lin, Yi-Wen
Lin, Wan-Jung
Hsieh, Ching-Liang
Liu, Hsu-Jan
Liu, Chung-Hsiang

Source

BioMed Research International

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-06-22

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Medicine

Abstract EN

Our previous study showed that mossy fiber sprouting can occur in the hippocampus region in rats 6 wk after kainic acid-induced epileptic seizure, and this mossy fiber sprouting can facilitate epileptogenesis.

Transcutaneous auricular vagal nerve stimulation (VNS), which is similar to cervical VNS, can reduce the occurrence of epileptic seizure in intractable epilepsy patients.

Greater parasympathetic nerve activity can be caused by 2 Hz electroacupuncture (EA).

Therefore, we investigated the effect of 2 Hz EA at ST-36-ST37 and at the ear on mossy fiber sprouting in kainic-treated Sprague-Dawley rats.

The results indicated that applying 2 Hz EA at ST36-ST37 and at the ear for 3 d per week over 6 consecutive weeks can ameliorate mossy fiber sprouting in the hippocampus region of rats.

These results indicated that applying 2 Hz EA at ST36-ST37 and at the ear might be beneficial for the treatment and prevention of epilepsy in humans.

American Psychological Association (APA)

Liu, Chung-Hsiang& Lin, Yi-Wen& Hsu, Hsin-Cheng& Liu, Hsu-Jan& Lin, Wan-Jung& Hsieh, Ching-Liang. 2014. Electroacupuncture at ST36-ST37 and at Ear Ameliorates Hippocampal Mossy Fiber Sprouting in Kainic Acid-Induced Epileptic Seizure Rats. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-496206

Modern Language Association (MLA)

Liu, Chung-Hsiang…[et al.]. Electroacupuncture at ST36-ST37 and at Ear Ameliorates Hippocampal Mossy Fiber Sprouting in Kainic Acid-Induced Epileptic Seizure Rats. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-496206

American Medical Association (AMA)

Liu, Chung-Hsiang& Lin, Yi-Wen& Hsu, Hsin-Cheng& Liu, Hsu-Jan& Lin, Wan-Jung& Hsieh, Ching-Liang. Electroacupuncture at ST36-ST37 and at Ear Ameliorates Hippocampal Mossy Fiber Sprouting in Kainic Acid-Induced Epileptic Seizure Rats. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-496206

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-496206