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Iron Chelation Therapy in Myelodysplastic Syndromes
Joint Authors
Messa, Emanuela
Cilloni, Daniela
Saglio, Giuseppe G.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Myelodysplastic syndromes (MDS) are a heterogeneous disorder of the hematopoietic stem cells, frequently characterized by anemia and transfusion dependency.
In low-risk patients, transfusion dependency can be long lasting, leading to iron overload.
Iron chelation therapy may be a therapeutic option for these patients, especially since the approval of oral iron chelators, which are easier to use and better accepted by the patients.
The usefulness of iron chelation in MDS patients is still under debate, mainly because of the lack of solid prospective clinical trials that should take place in the future.
This review aims to summarize what is currently known about the incidence and clinical consequences of iron overload in MDS patients and the state-of the-art of iron chelation therapy in this setting.
We also give an overview of clinical guidelines for chelation in MDS published to date and some perspectives for the future.
American Psychological Association (APA)
Messa, Emanuela& Cilloni, Daniela& Saglio, Giuseppe G.. 2010. Iron Chelation Therapy in Myelodysplastic Syndromes. Advances in Hematology،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-496240
Modern Language Association (MLA)
Messa, Emanuela…[et al.]. Iron Chelation Therapy in Myelodysplastic Syndromes. Advances in Hematology No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-496240
American Medical Association (AMA)
Messa, Emanuela& Cilloni, Daniela& Saglio, Giuseppe G.. Iron Chelation Therapy in Myelodysplastic Syndromes. Advances in Hematology. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-496240
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496240