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MicroRNA Expression in Salivary Supernatant of Patients with Pancreatic Cancer and Its Relationship with ZHENG
Joint Authors
Chen, Lian-Yu
Liu, Lu-Ming
Chen, Zhen
Wang, Peng
Gao, Song
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
In traditional Chinese medicine (TCM), diagnosis and prescriptions are based on the signs and symptoms which are recognized as ZHENG.
The cornerstone of TCM is to differentially treat one ZHENG from others, which is also known as syndrome differentiation, and this relies on the gathering of clinical information through inspection, auscultation and olfaction, inquiry, and palpation.
However, the biomolecular basis of the ZHENG remains unclear.
In this study, the expressions of 384 cancer-related miRNAs in salivary supernatant of patients with pancreatic cancer were assessed by miRNA polymerase chain reaction (PCR) array, and the different expression patterns of miRNA in three different groups of ZHENG were studied with use of real-time quantitative PCR (qRT-PCR).
Some miRNAs were found to be specifically expressed in some ZHENGs, for instance, miR-17, miR-21, and miR-181b in Shi-Re ZHENG and miR-196a in Pi-Xu ZHENG.
This indicates that these miRNAs may play important roles in different ZHENG condition.
Therefore, this study to some extent revealed the molecular basis of TCM ZHENG in pancreatic cancer.
American Psychological Association (APA)
Gao, Song& Chen, Lian-Yu& Wang, Peng& Liu, Lu-Ming& Chen, Zhen. 2014. MicroRNA Expression in Salivary Supernatant of Patients with Pancreatic Cancer and Its Relationship with ZHENG. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-496248
Modern Language Association (MLA)
Gao, Song…[et al.]. MicroRNA Expression in Salivary Supernatant of Patients with Pancreatic Cancer and Its Relationship with ZHENG. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-496248
American Medical Association (AMA)
Gao, Song& Chen, Lian-Yu& Wang, Peng& Liu, Lu-Ming& Chen, Zhen. MicroRNA Expression in Salivary Supernatant of Patients with Pancreatic Cancer and Its Relationship with ZHENG. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-496248
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496248