The Evaluation of the Body Weight Lowering Effects of Herbal Extract THI on Exercising Healthy Overweight Humans : A Randomized Double-Blind, Placebo-Controlled Trial
Joint Authors
Yoon, Yoosik
Cho, Soo Hyun
Yang, Young
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We investigated the effects of herbal extracts, a mixture of Scutellariae Radix and Platycodi Radix containing the active ingredients Baicalin and Saponin (target herbal ingredient (THI)), on lowering body weight.
The present study was a prospective, randomized, double-blind, and placebo-controlled trial carried out at the outpatient department of a hospital over a period of 2 months.
Group 1 patients (n=30) received THI, and group 2 patients (n=23) received placebo three times a day before meals.
Weight, waist circumference, BMI, total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, and glucose were measured at baseline and again at the 2nd month.
For safety evaluation, various hematological and biochemical parameters were assessed.
Values of mean change of weight in the THI-treated group were −1.16±1.41 kg and in the placebo-treated group were −0.24±1.70 kg, respectively.
The difference in mean change of weight in the THI-treated group compared with that in the placebo-treated group was statistically significant (P<0.05).
The incidence of subjective and objective adverse drug reactions was insignificant (P>0.05).
THI was statistically significant in its effectiveness on the weight loss.
American Psychological Association (APA)
Cho, Soo Hyun& Yoon, Yoosik& Yang, Young. 2013. The Evaluation of the Body Weight Lowering Effects of Herbal Extract THI on Exercising Healthy Overweight Humans : A Randomized Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-496414
Modern Language Association (MLA)
Cho, Soo Hyun…[et al.]. The Evaluation of the Body Weight Lowering Effects of Herbal Extract THI on Exercising Healthy Overweight Humans : A Randomized Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-496414
American Medical Association (AMA)
Cho, Soo Hyun& Yoon, Yoosik& Yang, Young. The Evaluation of the Body Weight Lowering Effects of Herbal Extract THI on Exercising Healthy Overweight Humans : A Randomized Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-496414
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496414