B-Cell Pathology in Juvenile Idiopathic Arthritis

Joint Authors

Wiegering, V.
Girschick, H. J.
Morbach, H.

Source

Arthritis

Issue

Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2010-12-02

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Diseases

Abstract EN

Juvenile Idiopathic Arthritis (JIA) is the most common cause of chronic arthritis in childhood and adolescents and encompasses a heterogeneous group of different diseases.

Due to the promising results of B-cell depleting therapies in rheumatoid arthritis the role of B-cells in autoimmune diseases has to be discussed in a new context.

Additionally, experiments in mouse models have shed new light on the antibody-independent role of B-cells in the development of autoimmune diseases.

In this review we will discuss the importance of B-cells in the pathogenesis of JIA appraising the question for an immunological basis of B-cell targeted therapy in JIA.

American Psychological Association (APA)

Wiegering, V.& Girschick, H. J.& Morbach, H.. 2010. B-Cell Pathology in Juvenile Idiopathic Arthritis. Arthritis،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-496566

Modern Language Association (MLA)

Wiegering, V.…[et al.]. B-Cell Pathology in Juvenile Idiopathic Arthritis. Arthritis No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-496566

American Medical Association (AMA)

Wiegering, V.& Girschick, H. J.& Morbach, H.. B-Cell Pathology in Juvenile Idiopathic Arthritis. Arthritis. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-496566

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-496566