B-Cell Pathology in Juvenile Idiopathic Arthritis
Joint Authors
Wiegering, V.
Girschick, H. J.
Morbach, H.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Juvenile Idiopathic Arthritis (JIA) is the most common cause of chronic arthritis in childhood and adolescents and encompasses a heterogeneous group of different diseases.
Due to the promising results of B-cell depleting therapies in rheumatoid arthritis the role of B-cells in autoimmune diseases has to be discussed in a new context.
Additionally, experiments in mouse models have shed new light on the antibody-independent role of B-cells in the development of autoimmune diseases.
In this review we will discuss the importance of B-cells in the pathogenesis of JIA appraising the question for an immunological basis of B-cell targeted therapy in JIA.
American Psychological Association (APA)
Wiegering, V.& Girschick, H. J.& Morbach, H.. 2010. B-Cell Pathology in Juvenile Idiopathic Arthritis. Arthritis،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-496566
Modern Language Association (MLA)
Wiegering, V.…[et al.]. B-Cell Pathology in Juvenile Idiopathic Arthritis. Arthritis No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-496566
American Medical Association (AMA)
Wiegering, V.& Girschick, H. J.& Morbach, H.. B-Cell Pathology in Juvenile Idiopathic Arthritis. Arthritis. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-496566
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496566