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Dopamine Dysregulation Syndrome and Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease
Joint Authors
De la Casa-Fages, Beatriz
Grandas, Francisco
Source
Neurology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Dopamine dysregulation syndrome is a complication of the dopaminergic treatment in Parkinson's disease that may be very disabling due to the negative impact that compulsive medication use may have on patients' social, psychological, and physical functioning.
The relationship between subthalamic nucleus deep brain stimulation and dopamine dysregulation syndrome in patients with Parkinson's disease remains unclear.
Deep brain stimulation may improve, worsen, or have no effect on preoperative dopamine dysregulation syndrome.
Moreover, dopamine dysregulation syndrome may appear for the first time after deep brain stimulation of the subthalamic nucleus.
The outcome of postoperative dopamine dysregulation syndrome is poor despite stimulation and medication adjustments.
Here we review the phenomenology and neurobiology of this disorder, discuss possible mechanisms that may underlie the diverse outcomes of dopamine dysregulation syndrome after subthalamic nucleus deep brain stimulation, and propose management strategies.
American Psychological Association (APA)
De la Casa-Fages, Beatriz& Grandas, Francisco. 2011. Dopamine Dysregulation Syndrome and Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease. Neurology Research International،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-496569
Modern Language Association (MLA)
De la Casa-Fages, Beatriz& Grandas, Francisco. Dopamine Dysregulation Syndrome and Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease. Neurology Research International No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-496569
American Medical Association (AMA)
De la Casa-Fages, Beatriz& Grandas, Francisco. Dopamine Dysregulation Syndrome and Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease. Neurology Research International. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-496569
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496569