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Reproductive Benefit of Oxidative Damage : An Oxidative Stress “Malevolence”?
Joint Authors
Milisav, Irina
Poljsak, Borut
Lampe, T.
Ostan, I.
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
High levels of reactive oxygen species (ROS) compared to antioxidant defenses are considered to play a major role in diverse chronic age-related diseases and aging.
Here we present an attempt to synthesize information about proximate oxidative processes in aging (relevant to free radical or oxidative damage hypotheses of aging) with an evolutionary scenario (credited here to Dawkins hypotheses) involving tradeoffs between the costs and benefits of oxidative stress to reproducing organisms.
Oxidative stress may be considered a biological imperfection; therefore, the Dawkins' theory of imperfect adaptation of beings to environment was applied to the role of oxidative stress in processes like famine and infectious diseases and their consequences at the molecular level such as mutations and cell signaling.
Arguments are presented that oxidative damage is not necessarily an evolutionary mistake but may be beneficial for reproduction; this may prevail over its harmfulness to health and longevity in evolution.
Thus, Dawkins' principle of biological “malevolence” may be an additional biological paradigm for explaining the consequences of oxidative stress.
American Psychological Association (APA)
Poljsak, Borut& Milisav, Irina& Lampe, T.& Ostan, I.. 2011. Reproductive Benefit of Oxidative Damage : An Oxidative Stress “Malevolence”?. Oxidative Medicine and Cellular Longevity،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-496657
Modern Language Association (MLA)
Poljsak, Borut…[et al.]. Reproductive Benefit of Oxidative Damage : An Oxidative Stress “Malevolence”?. Oxidative Medicine and Cellular Longevity No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-496657
American Medical Association (AMA)
Poljsak, Borut& Milisav, Irina& Lampe, T.& Ostan, I.. Reproductive Benefit of Oxidative Damage : An Oxidative Stress “Malevolence”?. Oxidative Medicine and Cellular Longevity. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-496657
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496657