Metabolic Engineering for Production of Biorenewable Fuels and Chemicals : Contributions of Synthetic Biology
Joint Authors
Ingram, Lonnie O.
Shanmugam, K. T.
Zhang, Xueli
Moore, Jonathan C.
Jarboe, Laura R.
Wang, Xuan
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-04-06
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Production of fuels and chemicals through microbial fermentation of plant material is a desirable alternative to petrochemical-based production.
Fermentative production of biorenewable fuels and chemicals requires the engineering of biocatalysts that can quickly and efficiently convert sugars to target products at a cost that is competitive with existing petrochemical-based processes.
It is also important that biocatalysts be robust to extreme fermentation conditions, biomass-derived inhibitors, and their target products.
Traditional metabolic engineering has made great advances in this area, but synthetic biology has contributed and will continue to contribute to this field, particularly with next-generation biofuels.
This work reviews the use of metabolic engineering and synthetic biology in biocatalyst engineering for biorenewable fuels and chemicals production, such as ethanol, butanol, acetate, lactate, succinate, alanine, and xylitol.
We also examine the existing challenges in this area and discuss strategies for improving biocatalyst tolerance to chemical inhibitors.
American Psychological Association (APA)
Jarboe, Laura R.& Zhang, Xueli& Wang, Xuan& Moore, Jonathan C.& Shanmugam, K. T.& Ingram, Lonnie O.. 2010. Metabolic Engineering for Production of Biorenewable Fuels and Chemicals : Contributions of Synthetic Biology. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-18.
https://search.emarefa.net/detail/BIM-496663
Modern Language Association (MLA)
Jarboe, Laura R.…[et al.]. Metabolic Engineering for Production of Biorenewable Fuels and Chemicals : Contributions of Synthetic Biology. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-18.
https://search.emarefa.net/detail/BIM-496663
American Medical Association (AMA)
Jarboe, Laura R.& Zhang, Xueli& Wang, Xuan& Moore, Jonathan C.& Shanmugam, K. T.& Ingram, Lonnie O.. Metabolic Engineering for Production of Biorenewable Fuels and Chemicals : Contributions of Synthetic Biology. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-18.
https://search.emarefa.net/detail/BIM-496663
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496663