The Efficacy and Safety of Rivaroxaban for Venous Thromboembolism Prophylaxis after Total Hip and Total Knee Arthroplasty
Joint Authors
Russell, Robert D.
Huo, Michael H.
Knight, Justin R.
Hotchkiss, William R.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-21
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Venous thromboembolism (VTE) is a common complication after total hip and total knee arthroplasty.
Currently used methods of VTE prophylaxis after these procedures have important limitations, including parenteral administration, and unpredictable plasma levels requiring frequent monitoring and dose adjustment leading to decreased patient compliance with recommended guidelines.
New oral anticoagulants have been demonstrated in clinical trials to be equally efficacious to enoxaparin and allow for fixed dosing without the need for monitoring.
Rivaroxaban is one of the new oral anticoagulants and is a direct factor Xa inhibitor that has demonstrated superior efficacy to that of enoxaparin.
However, the data also suggest that rivaroxaban has an increased risk of bleeding compared to enoxaparin.
This paper reviews the available data on the efficacy and safety of rivaroxaban for VTE prophylaxis after total hip and total knee arthroplasty.
American Psychological Association (APA)
Russell, Robert D.& Hotchkiss, William R.& Knight, Justin R.& Huo, Michael H.. 2013. The Efficacy and Safety of Rivaroxaban for Venous Thromboembolism Prophylaxis after Total Hip and Total Knee Arthroplasty. Thrombosis،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-496777
Modern Language Association (MLA)
Russell, Robert D.…[et al.]. The Efficacy and Safety of Rivaroxaban for Venous Thromboembolism Prophylaxis after Total Hip and Total Knee Arthroplasty. Thrombosis No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-496777
American Medical Association (AMA)
Russell, Robert D.& Hotchkiss, William R.& Knight, Justin R.& Huo, Michael H.. The Efficacy and Safety of Rivaroxaban for Venous Thromboembolism Prophylaxis after Total Hip and Total Knee Arthroplasty. Thrombosis. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-496777
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496777