Systematic Review and Meta-Analysis of 16 Randomized Clinical Trials of Radix Astragali and Its Prescriptions for Diabetic Retinopathy
Joint Authors
Zhang, Gai
Lu, Xuejing
Duan, Junguo
Zhang, Fuwen
Cheng, Lin
Ye, Hejiang
Zhou, Yi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-21
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Objective.
To evaluate the efficacy and safety of radix astragali and its prescriptions for diabetic retinopathy.
Methods.
A computer-based online and manual search was conducted for randomized controlled trials addressing radix astragali and its prescriptions for diabetic retinopathy.
Results.
16 RCTs involving 977 subjects and 1586 eyes were identified.
Meta-analysis indicated that the effect of radix astragali and its prescriptions in improving visual acuity and fundus manifestations, lowering FBG, TG, plasma viscosity, and RAI, was superior to that of control group (WMD or OR 0.20, 0.27, −0.26, −0.36, −0.93, −1.27; 95% CI [0.09, 0.30], [0.17, 0.40], [−0.51, 0.00], [−0.60, −0.12], [−1.67, −0.20], [−2.35, −0.19]; P<0.05, resp.).
In contrary, the efficacy of radix astragali and its prescriptions was not superior to those of control group in descending HbA1C and TC with WMD 0.45, −0.96 and 95% CI [−1.00, 1.90], [−2.19, 0.27], P>0.05, respectively.
GRADE software suggested that the studies were of low methodological quality.
Conclusion.
Radix astragali and its prescriptions were superior to other treatments for diabetic retinopathy in terms of improving visual acuity and fundus manifestations, reducing FBG, TG, RAI, and plasma viscosity.
The evaluated studies were of low methodological quality, indicating that the previous findings should be read with care.
American Psychological Association (APA)
Cheng, Lin& Zhang, Gai& Zhou, Yi& Lu, Xuejing& Zhang, Fuwen& Ye, Hejiang…[et al.]. 2013. Systematic Review and Meta-Analysis of 16 Randomized Clinical Trials of Radix Astragali and Its Prescriptions for Diabetic Retinopathy. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-496822
Modern Language Association (MLA)
Cheng, Lin…[et al.]. Systematic Review and Meta-Analysis of 16 Randomized Clinical Trials of Radix Astragali and Its Prescriptions for Diabetic Retinopathy. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-496822
American Medical Association (AMA)
Cheng, Lin& Zhang, Gai& Zhou, Yi& Lu, Xuejing& Zhang, Fuwen& Ye, Hejiang…[et al.]. Systematic Review and Meta-Analysis of 16 Randomized Clinical Trials of Radix Astragali and Its Prescriptions for Diabetic Retinopathy. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-496822
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496822