Relationship between Abdominal Pressure, Pulmonary Compliance, and Cardiac Preload in a Porcine Model
Joint Authors
Wauters, Joost
Wilmer, Alexander
McLaughlin, Myles
Hermans, Greet
Malbrain, Manu
Claus, Piet
Brosens, Nathalie
Source
Critical Care Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Rationale.
Elevated intra-abdominal pressure (IAP) may compromise respiratory and cardiovascular function by abdomino-thoracic pressure transmission.
We aimed (1) to study the effects of elevated IAP on pleural pressure, (2) to understand the implications for lung and chest wall compliances and (3) to determine whether volumetric filling parameters may be more accurate than classical pressure-based filling pressures for preload assessment in the setting of elevated IAP.
Methods.
In eleven pigs, IAP was increased stepwise from 6 to 30 mmHg.
Hemodynamic, esophageal, and pulmonary pressures were recorded.
Results.
17% (end-expiratory) to 62% (end-inspiratory) of elevated IAP was transmitted to the thoracic compartment.
Respiratory system compliance decreased significantly with elevated IAP and chest wall compliance decreased.
Central venous and pulmonary wedge pressure increased with increasing IAP and correlated inversely (r=-0.31) with stroke index (SI).
Global end-diastolic volume index was unaffected by IAP and correlated best with SI (r=0.52).
Conclusions.
Increased IAP is transferred to the thoracic compartment and results in a decreased respiratory system compliance due to decreased chest wall compliance.
Volumetric filling parameters and transmural filling pressures are clearly superior to classical cardiac filling pressures in the assessment of cardiac preload during elevated IAP.
American Psychological Association (APA)
Wauters, Joost& Claus, Piet& Brosens, Nathalie& McLaughlin, Myles& Hermans, Greet& Malbrain, Manu…[et al.]. 2012. Relationship between Abdominal Pressure, Pulmonary Compliance, and Cardiac Preload in a Porcine Model. Critical Care Research and Practice،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-496862
Modern Language Association (MLA)
Wauters, Joost…[et al.]. Relationship between Abdominal Pressure, Pulmonary Compliance, and Cardiac Preload in a Porcine Model. Critical Care Research and Practice No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-496862
American Medical Association (AMA)
Wauters, Joost& Claus, Piet& Brosens, Nathalie& McLaughlin, Myles& Hermans, Greet& Malbrain, Manu…[et al.]. Relationship between Abdominal Pressure, Pulmonary Compliance, and Cardiac Preload in a Porcine Model. Critical Care Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-496862
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496862