![](/images/graphics-bg.png)
Cellular-Based Immunotherapies for Patients with Glioblastoma Multiforme
Joint Authors
Stockhammer, Florian
Schmitt, Michael
Xu, Xun
Source
Clinical and Developmental Immunology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-28
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Treatment of patients with glioblastoma multiforme (GBM) remains to be a challenge with a median survival of 14.6 months following diagnosis.
Standard treatment options include surgery, radiation therapy, and systemic chemotherapy with temozolomide.
Despite the fact that the brain constitutes an immunoprivileged site, recent observations after immunotherapies with lysate from autologous tumor cells pulsed on dendritic cells (DCs), peptides, protein, messenger RNA, and cytokines suggest an immunological and even clinical response from immunotherapies.
Given this plethora of immunomodulatory therapies, this paper gives a structure overview of the state-of-the art in the field.
Particular emphasis was also put on immunogenic antigens as potential targets for a more specific stimulation of the immune system against GBM.
American Psychological Association (APA)
Xu, Xun& Stockhammer, Florian& Schmitt, Michael. 2012. Cellular-Based Immunotherapies for Patients with Glioblastoma Multiforme. Clinical and Developmental Immunology،Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-496960
Modern Language Association (MLA)
Xu, Xun…[et al.]. Cellular-Based Immunotherapies for Patients with Glioblastoma Multiforme. Clinical and Developmental Immunology No. 2012 (2012), pp.1-15.
https://search.emarefa.net/detail/BIM-496960
American Medical Association (AMA)
Xu, Xun& Stockhammer, Florian& Schmitt, Michael. Cellular-Based Immunotherapies for Patients with Glioblastoma Multiforme. Clinical and Developmental Immunology. 2012. Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-496960
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496960