Voltammetric Determination of Acetaminophen in the Presence of Codeine and Ascorbic Acid at Layer-by-Layer MWCNTHydroquinone Sulfonic Acid-Overoxidized Polypyrrole Modified Glassy Carbon Electrode
Joint Authors
Saberi, Reyhaneh-Sadat
Shahrokhian, Saeed
Source
International Journal of Electrochemistry
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-13
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
A very sensitive electrochemical sensor constructed of a glassy carbon electrode modified with a layer-by-layer MWCNT/doped-overoxidized polypyrrole (oppy/MWCNT /GCE) was used for the determination of acetaminophen (AC) in the presence of codeine and ascorbic acid (AA).
In comparison to the bare glassy carbon electrode, a considerable shift in the peak potential together with an increase in the peak current was observed for AC on the surface of oppy/MWCNT/GCE, which can be related to the enlarged microscopic surface area of the electrode.
The effect of the experimental conditions on the electrode response, such as types of counter ion, pyrrole and counter ion concentration, potential and number of cycles in the polymerization procedure, amount of MWCNT, and the pH, were investigated.
Under the optimized conditions, the calibration curve was obtained over two concentration ranges of 2 × 10−7–6 × 10−6 M and 4 × 10−5–1 × 10−4 M of AC with a linear correlation coefficient (R2) of 0.9959 and 0.9947, respectively.
The estimated detection limit (3σ) for AC was obtained as 5 × 10−8 M.
The developed method was successfully applied to analyze the pharmaceutical preparations of AC, and a recovery of 95% with a relative standard deviation of 0.98% was obtained for AC.
American Psychological Association (APA)
Shahrokhian, Saeed& Saberi, Reyhaneh-Sadat. 2011. Voltammetric Determination of Acetaminophen in the Presence of Codeine and Ascorbic Acid at Layer-by-Layer MWCNTHydroquinone Sulfonic Acid-Overoxidized Polypyrrole Modified Glassy Carbon Electrode. International Journal of Electrochemistry،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-496971
Modern Language Association (MLA)
Shahrokhian, Saeed& Saberi, Reyhaneh-Sadat. Voltammetric Determination of Acetaminophen in the Presence of Codeine and Ascorbic Acid at Layer-by-Layer MWCNTHydroquinone Sulfonic Acid-Overoxidized Polypyrrole Modified Glassy Carbon Electrode. International Journal of Electrochemistry No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-496971
American Medical Association (AMA)
Shahrokhian, Saeed& Saberi, Reyhaneh-Sadat. Voltammetric Determination of Acetaminophen in the Presence of Codeine and Ascorbic Acid at Layer-by-Layer MWCNTHydroquinone Sulfonic Acid-Overoxidized Polypyrrole Modified Glassy Carbon Electrode. International Journal of Electrochemistry. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-496971
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-496971