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A Review of Translational Animal Models for Knee Osteoarthritis
Joint Authors
Kuroki, Keiichi
Stoker, Aaron M.
Cook, James L.
Sherman, Seth L.
Gregory, Martin H.
Capito, Nicholas
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-27
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Knee osteoarthritis remains a tremendous public health concern, both in terms of health-related quality of life and financial burden of disease.
Translational research is a critical step towards understanding and mitigating the long-term effects of this disease process.
Animal models provide practical and clinically relevant ways to study both the natural history and response to treatment of knee osteoarthritis.
Many factors including size, cost, and method of inducing osteoarthritis are important considerations for choosing an appropriate animal model.
Smaller animals are useful because of their ease of use and cost, while larger animals are advantageous because of their anatomical similarity to humans.
This evidence-based review will compare and contrast several different animal models for knee osteoarthritis.
Our goal is to inform the clinician about current research models, in order to facilitate the transfer of knowledge from the “bench” to the “bedside.”
American Psychological Association (APA)
Gregory, Martin H.& Capito, Nicholas& Kuroki, Keiichi& Stoker, Aaron M.& Cook, James L.& Sherman, Seth L.. 2012. A Review of Translational Animal Models for Knee Osteoarthritis. Arthritis،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-497003
Modern Language Association (MLA)
Gregory, Martin H.…[et al.]. A Review of Translational Animal Models for Knee Osteoarthritis. Arthritis No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-497003
American Medical Association (AMA)
Gregory, Martin H.& Capito, Nicholas& Kuroki, Keiichi& Stoker, Aaron M.& Cook, James L.& Sherman, Seth L.. A Review of Translational Animal Models for Knee Osteoarthritis. Arthritis. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-497003
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497003