The Sensitivity and Specificity of Potassium Hydroxide Smear and Fungal Culture Relative to Clinical Assessment in the Evaluation of Tinea Pedis : A Pooled Analysis
Joint Authors
Levitt, Barrie H.
Levitt, Jacob Oren
Akhavan, Arash
Yanofsky, Howard
Source
Dermatology Research and Practice
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
There are relatively few studies published examining the sensitivity and specificity of potassium hydroxide (KOH) smear and fungal culture examination of tinea pedis.
Objective.
To evaluate the sensitivity and specificity of KOH smear and fungal culture for diagnosing tinea pedis.
Methods.
A pooled analysis of data from five similarly conducted bioequivalence trials for antifungal drugs was performed.
Data from 460 patients enrolled in the vehicle arms of these studies with clinical diagnosis of tinea pedis supported by positive fungal culture were analyzed 6 weeks after initiation of the study to determine the sensitivity and specificity of KOH smear and fungal culture.
Results.
Using clinical assessment as the gold standard, the sensitivities for KOH smear and culture were 73.3% (95% CI: 66.3 to 79.5%) and 41.7% (34.6 to 49.1%), respectively.
The respective specificities for culture and KOH smear were 77.7% (72.2 to 82.5%) and 42.5% (36.6 to 48.6%).
Conclusion.
KOH smear and fungal culture are complementary diagnostic tests for tinea pedis, with the former being the more sensitive test of the two, and the latter being more specific.
American Psychological Association (APA)
Levitt, Jacob Oren& Levitt, Barrie H.& Akhavan, Arash& Yanofsky, Howard. 2010. The Sensitivity and Specificity of Potassium Hydroxide Smear and Fungal Culture Relative to Clinical Assessment in the Evaluation of Tinea Pedis : A Pooled Analysis. Dermatology Research and Practice،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-497020
Modern Language Association (MLA)
Levitt, Jacob Oren…[et al.]. The Sensitivity and Specificity of Potassium Hydroxide Smear and Fungal Culture Relative to Clinical Assessment in the Evaluation of Tinea Pedis : A Pooled Analysis. Dermatology Research and Practice No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-497020
American Medical Association (AMA)
Levitt, Jacob Oren& Levitt, Barrie H.& Akhavan, Arash& Yanofsky, Howard. The Sensitivity and Specificity of Potassium Hydroxide Smear and Fungal Culture Relative to Clinical Assessment in the Evaluation of Tinea Pedis : A Pooled Analysis. Dermatology Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-497020
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497020