Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients
Joint Authors
Thang, P.
Phan, D. V.
Östenson, C. G.
Huyen, V. T. T.
Hoa, N. K.
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aims.
To evaluate the effect of the traditional Vietnamese herb Gynostemma pentaphyllum tea on insulin sensitivity in drug-naïve type 2 diabetic patients.
Methods.
Patients received GP or placebo tea 6 g daily for four weeks and vice versa with a 2-week wash-out period.
At the end of each period, a somatostatin-insulin-glucose infusion test (SIGIT) was performed to evaluate the insulin sensitivity.
Fasting plasma glucose (FPG), HbA1C, and oral glucose tolerance tests and insulin levels were measured before, during, and after the treatment.
Results.
FPG and steady-state plasma glucose (SIGIT mean) were lower after GP treatment compared to placebo treatment (P<0.001).
The levels of FPG in the control group were slightly reduced to 0.2±1.5 versus 1.9±1.0 mmol/L in GP group (P<0.001), and the effect on FPG was reversed after exchanging treatments.
The glycometabolic improvements were achieved without any major change of circulating insulin levels.
There were no changes in lipids, body measurements, blood pressure, and no reported hypoglycemias or acute adverse effects regarding kidney and liver parameters.
Conclusion.
The results of this study suggested that the GP tea exerted antidiabetic effect by improving insulin sensitivity.
American Psychological Association (APA)
Huyen, V. T. T.& Phan, D. V.& Thang, P.& Hoa, N. K.& Östenson, C. G.. 2013. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients. Journal of Nutrition and Metabolism،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-497064
Modern Language Association (MLA)
Huyen, V. T. T.…[et al.]. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients. Journal of Nutrition and Metabolism No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-497064
American Medical Association (AMA)
Huyen, V. T. T.& Phan, D. V.& Thang, P.& Hoa, N. K.& Östenson, C. G.. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients. Journal of Nutrition and Metabolism. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-497064
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497064