Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study
Joint Authors
Kern, Andrew M.
Segal, Neil A.
Anderson, Donald D.
Torner, James C.
Lynch, John A.
Nevitt, Michael C.
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Recent findings suggest that contact stress is a potent predictor of subsequent symptomatic osteoarthritis development in the knee.
However, much larger numbers of knees (likely on the order of hundreds, if not thousands) need to be reliably analyzed to achieve the statistical power necessary to clarify this relationship.
This study assessed the reliability of new semiautomated computational methods for estimating contact stress in knees from large population-based cohorts.
Ten knees of subjects from the Multicenter Osteoarthritis Study were included.
Bone surfaces were manually segmented from sequential 1.0 Tesla magnetic resonance imaging slices by three individuals on two nonconsecutive days.
Four individuals then registered the resulting bone surfaces to corresponding bone edges on weight-bearing radiographs, using a semi-automated algorithm.
Discrete element analysis methods were used to estimate contact stress distributions for each knee.
Segmentation and registration reliabilities (day-to-day and interrater) for peak and mean medial and lateral tibiofemoral contact stress were assessed with Shrout-Fleiss intraclass correlation coefficients (ICCs).
The segmentation and registration steps of the modeling approach were found to have excellent day-to-day (ICC 0.93–0.99) and good inter-rater reliability (0.84–0.97).
This approach for estimating compartment-specific tibiofemoral contact stress appears to be sufficiently reliable for use in large population-based cohorts.
American Psychological Association (APA)
Anderson, Donald D.& Segal, Neil A.& Kern, Andrew M.& Nevitt, Michael C.& Torner, James C.& Lynch, John A.. 2012. Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study. Computational and Mathematical Methods in Medicine،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-497160
Modern Language Association (MLA)
Anderson, Donald D.…[et al.]. Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study. Computational and Mathematical Methods in Medicine No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-497160
American Medical Association (AMA)
Anderson, Donald D.& Segal, Neil A.& Kern, Andrew M.& Nevitt, Michael C.& Torner, James C.& Lynch, John A.. Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study. Computational and Mathematical Methods in Medicine. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-497160
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497160