Potential Inaccuracies in Chloride Measurements in Patients with Severe Metabolic Acidosis
Joint Authors
Maeda, Sayako
Makiishi, Tetsuya
Konishi, Takashi
Yamamoto, Shinya
Yoshioka, Keiko
Mitsuhashi, Ryuichi
Hirose, Kunihiko
Nishimura, Naomasa
Source
International Journal of Nephrology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
To address the cause(s) of the significant differences in chloride (Cl-) concentrations between point-of-care blood gas analyzers and central laboratory analyzers.
Methods.
Cl- concentrations measured simultaneously by a blood gas analyzer (ABL800 FLEX) and a central laboratory analyzer (Hitachi7600) were collected in patients with severe acidemia (pH<7.20) (n=32) and were examined for correlations between differences in Cl- and factors associated with the acid-base status.
Cl- concentrations were measured with both analyzers for samples with different concentrations of lactate, inorganic phosphate, or bicarbonate (HCO3 −).
Results.
The differences in Cl- concentrations were correlated with HCO3 − concentrations (r=0.72, P<0.0001) and anion gap (r=0.69, P<0.0001).
Only the addition of HCO3 − proportionately increased Cl- levels measured by a Hitachi7600, but it did not affect those measured by an ABL800FLEX.
Conclusion.
Cl- measurements with some analyzers may be influenced by HCO3 − concentrations, which could result in the observed discrepancies.
American Psychological Association (APA)
Makiishi, Tetsuya& Nishimura, Naomasa& Yoshioka, Keiko& Yamamoto, Shinya& Mitsuhashi, Ryuichi& Maeda, Sayako…[et al.]. 2012. Potential Inaccuracies in Chloride Measurements in Patients with Severe Metabolic Acidosis. International Journal of Nephrology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-497233
Modern Language Association (MLA)
Makiishi, Tetsuya…[et al.]. Potential Inaccuracies in Chloride Measurements in Patients with Severe Metabolic Acidosis. International Journal of Nephrology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-497233
American Medical Association (AMA)
Makiishi, Tetsuya& Nishimura, Naomasa& Yoshioka, Keiko& Yamamoto, Shinya& Mitsuhashi, Ryuichi& Maeda, Sayako…[et al.]. Potential Inaccuracies in Chloride Measurements in Patients with Severe Metabolic Acidosis. International Journal of Nephrology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-497233
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497233