Some Immunohormonal Changes in Experimentally Pregnant Toxemic Goats
Joint Authors
Hefnawy, Abd-Elghany
Youssef, Seham
Shousha, Saad
Source
Veterinary Medicine International
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-16
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Pregnancy toxemia was induced in nine pregnant goat does with twins by the stress of fasting with access to water in late pregnancy to investigate the effect of pregnancy toxemia on immunoglobulins (IgA, IgM, and IgG), cortisol, insulin, thyroid, and growth hormones and their correlations with the plasma levels of glucose and β-Hydroxybutyrate.
Plasma samples were collected at 0, 12, 24, 36, 48, and 72 hours after induction of pregnancy toxemia.
The result revealed that experimental animals developed neurological findings with convulsions and acetone odor from the mouth with recumbency after 72 hours.
Laboratory findings showed a significant increase in β-Hydroxybutyrate, cortisol, and insulin while there were significant decreases in glucose, thyroid, and immunoglobulins (IgA, IgM, and IgG).
Plasma glucose concentrations had significant negative correlations with β-hydroxybutyrate, cortisol, and insulin while the correlations were significantly positive with immunoglobulins and thyroid hormone.
Plasma β-hydroxybutyrate concentration was significantly positively correlated with cortisol and negatively correlated with immunoglobulins, insulin, and thyroid hormone.
From this study we can conclude that pregnancy toxemia might affect humoral immune responses as well as insulin, cortisol, and thyroid hormones.
Moreover, insulin might have a compensatory role to increase suppressive effect on ketogenesis in experimentally pregnant toxemic goats.
American Psychological Association (APA)
Hefnawy, Abd-Elghany& Youssef, Seham& Shousha, Saad. 2010. Some Immunohormonal Changes in Experimentally Pregnant Toxemic Goats. Veterinary Medicine International،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-497243
Modern Language Association (MLA)
Hefnawy, Abd-Elghany…[et al.]. Some Immunohormonal Changes in Experimentally Pregnant Toxemic Goats. Veterinary Medicine International No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-497243
American Medical Association (AMA)
Hefnawy, Abd-Elghany& Youssef, Seham& Shousha, Saad. Some Immunohormonal Changes in Experimentally Pregnant Toxemic Goats. Veterinary Medicine International. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-497243
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497243