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Extraction of Parquat from Blood by Clinoptilolite
Joint Authors
Shetab-Boushehri, Seyed Vahid
Aghaii-Afshar, Mohammad-Amin
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Paraquat is a bipyridyl herbicide and organic divalent cation which due to its high polarity and water solubility cannot be readily extracted by common organic solvents from body fluids.
Dithionite color test for qualitative and quantitative determination of paraquat in urine has been proposed and used for many years.
Although some methods were proposed for solvent extraction of paraquat from blood, they are less practical in clinical laboratories and lack high extraction recovery.
Clinoptilolite is a highly porous natural zeolite with cation-exchange property and high surface area.
In the present work, extraction of paraquat from human blood by clinoptilolite was investigated and compared with Amberlite CG-50 I, a well-known weak cation-exchanger.
Blood paraquat was adsorbed by adsorbents (clinoptilolite or Amberlite) and extracted from them by saturated sodium chloride solution.
Extracted paraquat was spectrophotometrically measured by means of sodium dithionite reagent at 394.5 nm.
Recovery, limit of detection, considering signal-to-noise (S/N) ratio of 3, and limit of quantification, regarding S/N of 10, of paraquat extraction by clinoptilolite and Amberlite CG-50 were 81.7% ± 3.4%, 0.58 μg, and 1.93 μg and 83.6% ± 3.2%, 0.49 μg, and 1.63 μg, respectively.
Repeatabilities (within-laboratory error) of paraquat extraction by clinoptilolite and Amberlite CG-50 I were 7.1% and 6.3%, respectively.
American Psychological Association (APA)
Aghaii-Afshar, Mohammad-Amin& Shetab-Boushehri, Seyed Vahid. 2014. Extraction of Parquat from Blood by Clinoptilolite. Advances in Toxicology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-497272
Modern Language Association (MLA)
Aghaii-Afshar, Mohammad-Amin& Shetab-Boushehri, Seyed Vahid. Extraction of Parquat from Blood by Clinoptilolite. Advances in Toxicology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-497272
American Medical Association (AMA)
Aghaii-Afshar, Mohammad-Amin& Shetab-Boushehri, Seyed Vahid. Extraction of Parquat from Blood by Clinoptilolite. Advances in Toxicology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-497272
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497272