Microcirculatory Changes in Term Newborns with Suspected Infection : An Observational Prospective Study
Joint Authors
Alba-Alejandre, Irene
Hiedl, Stephan
Genzel-Boroviczény, Orsolya
Source
International Journal of Pediatrics
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
In adults severely disturbed microcirculatory flow can be observed by Orthogonal Polarized Spectral (OPS) imaging techniques during sepsis.
Therefore we set out to assess for microcirculatory changes in term newborns with suspected early onset infection using OPS.
Methods.
OPS images were obtained prospectively from the vascular bed of the ear conch and upper arm of 47 newborns on their 1st, 2nd, and 3rd day of life.
OPS sequences were analyzed semiquantitatively offline and blinded to clinical status of the infant.
Flow in vessels was classified as continuous or noncontinuous flow and given as proportion of total vessels per image as in the studies in adults.
Results.
The proportion of vessels with continuous flow was significantly lower in the infants with infection (69% [56–81] versus 90% [87–94] (P=0.0003)).
None of the infants with infection was in shock or severely septic.
Conclusion.
In term neonates the microcirculatory flow is impaired in a large proportion of vessels even in mild to moderate infection.
These changes can be observed at the onset of disease at the external ear, an optimal site for microcirculatory measurements in term infants.
American Psychological Association (APA)
Alba-Alejandre, Irene& Hiedl, Stephan& Genzel-Boroviczény, Orsolya. 2013. Microcirculatory Changes in Term Newborns with Suspected Infection : An Observational Prospective Study. International Journal of Pediatrics،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-497282
Modern Language Association (MLA)
Alba-Alejandre, Irene…[et al.]. Microcirculatory Changes in Term Newborns with Suspected Infection : An Observational Prospective Study. International Journal of Pediatrics No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-497282
American Medical Association (AMA)
Alba-Alejandre, Irene& Hiedl, Stephan& Genzel-Boroviczény, Orsolya. Microcirculatory Changes in Term Newborns with Suspected Infection : An Observational Prospective Study. International Journal of Pediatrics. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-497282
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497282