Drug Delivery Implants in the Treatment of Vitreous Inflammation
Joint Authors
Christoforidis, John Byron
Wang, Jillian
Jiang, Angela
Joshi, Malav
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The eye is a model organ for the local delivery of therapeutics.
This proves beneficial when treating vitreous inflammation and other ophthalmic pathologies.
The chronicity of certain diseases, however, limits the effectiveness of locally administered drugs.
To maintain such treatments often requires frequent office visits and can result in increased risk of infection and toxicity to the patient.
This paper focuses on the implantable devices and particulate drug delivery systems that are currently being implemented and investigated to overcome these challenges.
Implants currently on the market or undergoing clinical trials include those made of nonbiodegradable polymers, containing ganciclovir, fluocinolone acetonide, triamcinolone acetonide, and ranibizumab, and biodegradable polymers, containing dexamethasone, triamcinolone acetonide, and ranibizumab.
Investigational intravitreal implants and particulate drug delivery systems, such as nanoparticles, microparticles, and liposomes, are also explored in this review article.
American Psychological Association (APA)
Wang, Jillian& Jiang, Angela& Joshi, Malav& Christoforidis, John Byron. 2013. Drug Delivery Implants in the Treatment of Vitreous Inflammation. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-497434
Modern Language Association (MLA)
Wang, Jillian…[et al.]. Drug Delivery Implants in the Treatment of Vitreous Inflammation. Mediators of Inflammation No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-497434
American Medical Association (AMA)
Wang, Jillian& Jiang, Angela& Joshi, Malav& Christoforidis, John Byron. Drug Delivery Implants in the Treatment of Vitreous Inflammation. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-497434
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497434