Drug Delivery Implants in the Treatment of Vitreous Inflammation

Joint Authors

Christoforidis, John Byron
Wang, Jillian
Jiang, Angela
Joshi, Malav

Source

Mediators of Inflammation

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-09-28

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Diseases

Abstract EN

The eye is a model organ for the local delivery of therapeutics.

This proves beneficial when treating vitreous inflammation and other ophthalmic pathologies.

The chronicity of certain diseases, however, limits the effectiveness of locally administered drugs.

To maintain such treatments often requires frequent office visits and can result in increased risk of infection and toxicity to the patient.

This paper focuses on the implantable devices and particulate drug delivery systems that are currently being implemented and investigated to overcome these challenges.

Implants currently on the market or undergoing clinical trials include those made of nonbiodegradable polymers, containing ganciclovir, fluocinolone acetonide, triamcinolone acetonide, and ranibizumab, and biodegradable polymers, containing dexamethasone, triamcinolone acetonide, and ranibizumab.

Investigational intravitreal implants and particulate drug delivery systems, such as nanoparticles, microparticles, and liposomes, are also explored in this review article.

American Psychological Association (APA)

Wang, Jillian& Jiang, Angela& Joshi, Malav& Christoforidis, John Byron. 2013. Drug Delivery Implants in the Treatment of Vitreous Inflammation. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-497434

Modern Language Association (MLA)

Wang, Jillian…[et al.]. Drug Delivery Implants in the Treatment of Vitreous Inflammation. Mediators of Inflammation No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-497434

American Medical Association (AMA)

Wang, Jillian& Jiang, Angela& Joshi, Malav& Christoforidis, John Byron. Drug Delivery Implants in the Treatment of Vitreous Inflammation. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-497434

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-497434