Ecofriendly and Facile One-Pot Multicomponent Synthesis of Thiopyrimidines under Microwave Irradiation
Joint Authors
Sahoo, Biswa Mohan
Panda, Jnyanaranjan
Ravi Kumar, B. V. V.
Dinda, S. C.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Abstract EN
A rapid, improved, and ecofriendly synthesis of thiopyrimidines is carried out via one-pot multicomponent reaction of ethylcyanoacetate, substituted benzaldehydes, and thiourea in presence of ethanolic K2CO3 using microwave irradiation heating method.
Excellent yields, shorter reaction time, and easy workup are the major advantageous features of this green protocol.
So the application of multicomponent reactions involves the combination of multiple starting materials with different functional groups leading to the highly efficient and environmentally friendly construction of multifunctional drug molecules.
The structures of the newly synthesized products were assigned on the basis of IR and 1HNMR spectral data.
American Psychological Association (APA)
Sahoo, Biswa Mohan& Ravi Kumar, B. V. V.& Panda, Jnyanaranjan& Dinda, S. C.. 2013. Ecofriendly and Facile One-Pot Multicomponent Synthesis of Thiopyrimidines under Microwave Irradiation. Journal of Nanoparticles،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-497453
Modern Language Association (MLA)
Sahoo, Biswa Mohan…[et al.]. Ecofriendly and Facile One-Pot Multicomponent Synthesis of Thiopyrimidines under Microwave Irradiation. Journal of Nanoparticles No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-497453
American Medical Association (AMA)
Sahoo, Biswa Mohan& Ravi Kumar, B. V. V.& Panda, Jnyanaranjan& Dinda, S. C.. Ecofriendly and Facile One-Pot Multicomponent Synthesis of Thiopyrimidines under Microwave Irradiation. Journal of Nanoparticles. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-497453
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497453