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Production of Lipid Microparticles Magnetically Active by a Supercritical Fluid-Based Process
Joint Authors
Bertucco, Alberto
Campolmi, Chiara
Vezzù, Keti
Source
International Journal of Chemical Engineering
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-08-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Engineering Sciences and Information Technology
Abstract EN
An original technique, based on supercritical CO2 and on the particles from gas saturated solution (PGSS) micronization method, was developed to obtain magnetically active lipid microparticles.
Magnetite nanoparticles (MNPs) were encapsulated into triestearin and phosphatidylcholine mixtures to increase their biocompatibility for future applications in the fields of biomedical diagnostics and therapeutic medications.
The lipid particles produced were characterized to determine size and size distribution, and to confirm the encapsulation of MNP.
The mean size was in the range of 200–800 nm.
The possibility to drive these magnetically active particles by an external magnet was demonstrated in a simple apparatus simulating a vessel of the circulatory system.
The results obtained indicate that the modified PGSS technique is suitable to produce lipid microparticles with magnetic activity for possible use in medical applications.
American Psychological Association (APA)
Vezzù, Keti& Campolmi, Chiara& Bertucco, Alberto. 2009. Production of Lipid Microparticles Magnetically Active by a Supercritical Fluid-Based Process. International Journal of Chemical Engineering،Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-497483
Modern Language Association (MLA)
Vezzù, Keti…[et al.]. Production of Lipid Microparticles Magnetically Active by a Supercritical Fluid-Based Process. International Journal of Chemical Engineering No. 2009 (2009), pp.1-9.
https://search.emarefa.net/detail/BIM-497483
American Medical Association (AMA)
Vezzù, Keti& Campolmi, Chiara& Bertucco, Alberto. Production of Lipid Microparticles Magnetically Active by a Supercritical Fluid-Based Process. International Journal of Chemical Engineering. 2009. Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-497483
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497483