Effects of Radix Adenophorae and Cyclosporine A on an OVA-Induced Murine Model of Asthma by Suppressing to T Cells Activity, Eosinophilia, and Bronchial Hyperresponsiveness
Joint Authors
Kim, Seung-Hyung
Lee, Young-Cheol
Roh, Seong-Soo
Seo, Young-Bae
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-03-18
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The present study is performed to investigate the inhibitory effects of Radix Adenophorae extract (RAE) on ovalbumin-induced asthma murine model.
To study the anti-inflammatory and antiasthmatic effects of RAE, we examined the development of pulmonary eosinophilic inflammation and inhibitory effects of T cells in murine by RAE and cyclosporine A (CsA).
We examined determination of airway hyperresponsiveness, flow cytometric analysis (FACS), enzyme-linked immunosorbent assay (ELISA), quantitative real time (PCR), hematoxylin-eosin staining, and Masson trichrome staining in lung tissue, lung weight, total cells, and eosinophil numbers in lung tissue.
We demonstrated how RAE suppressed development on inflammation and decreased airway damage.
American Psychological Association (APA)
Roh, Seong-Soo& Kim, Seung-Hyung& Lee, Young-Cheol& Seo, Young-Bae. 2008. Effects of Radix Adenophorae and Cyclosporine A on an OVA-Induced Murine Model of Asthma by Suppressing to T Cells Activity, Eosinophilia, and Bronchial Hyperresponsiveness. Mediators of Inflammation،Vol. 2008, no. 2008, pp.1-11.
https://search.emarefa.net/detail/BIM-497504
Modern Language Association (MLA)
Roh, Seong-Soo…[et al.]. Effects of Radix Adenophorae and Cyclosporine A on an OVA-Induced Murine Model of Asthma by Suppressing to T Cells Activity, Eosinophilia, and Bronchial Hyperresponsiveness. Mediators of Inflammation No. 2008 (2008), pp.1-11.
https://search.emarefa.net/detail/BIM-497504
American Medical Association (AMA)
Roh, Seong-Soo& Kim, Seung-Hyung& Lee, Young-Cheol& Seo, Young-Bae. Effects of Radix Adenophorae and Cyclosporine A on an OVA-Induced Murine Model of Asthma by Suppressing to T Cells Activity, Eosinophilia, and Bronchial Hyperresponsiveness. Mediators of Inflammation. 2008. Vol. 2008, no. 2008, pp.1-11.
https://search.emarefa.net/detail/BIM-497504
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497504