Comparison between Airway Responses to High versus Low Molecular Weight Compounds in Occupational Asthma
Joint Authors
Vagaggini, B.
Bacci, E.
Melosini, L.
De Santis, M.
Paggiaro, P. L.
Di Franco, A.
Novelli, F.
Talini, D.
Dente, F. L.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-25
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Occupational asthma (OA) is a heterogeneous disease, and the characteristics of the sensitizer responsible for OA may induce different clinical, functional, and biological manifestations.
We examined the characteristics of 74 patients with OA induced by low molecular weight compounds (LMWC) or by high molecular weight compounds (HMWC) and diagnosed by specific inhalation challenge (SIC).
Patients with OA induced by LMWC had a longer occupational exposure before the beginning of symptoms, a lower sputum eosinophilia, and a higher prevalence of late airway response (LAR), in comparison with patients with OA induced by HMWC.
Pulmonary function tended to be poorer and atopy tended to be less frequent in LMWC-induced OA than in HMWC-induced OA.
These data confirm and extend previous observations showing that the characteristics of the specific sensitizer inducing OA may determine different clinical, functional, and biological features, probably related to the difference pathogenetic mechanisms underlying these different types of OA.
American Psychological Association (APA)
Talini, D.& Novelli, F.& Bacci, E.& Dente, F. L.& De Santis, M.& Di Franco, A.…[et al.]. 2011. Comparison between Airway Responses to High versus Low Molecular Weight Compounds in Occupational Asthma. Journal of Allergy،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-497511
Modern Language Association (MLA)
Talini, D.…[et al.]. Comparison between Airway Responses to High versus Low Molecular Weight Compounds in Occupational Asthma. Journal of Allergy No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-497511
American Medical Association (AMA)
Talini, D.& Novelli, F.& Bacci, E.& Dente, F. L.& De Santis, M.& Di Franco, A.…[et al.]. Comparison between Airway Responses to High versus Low Molecular Weight Compounds in Occupational Asthma. Journal of Allergy. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-497511
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497511