Engineering a Biocompatible Scaffold with Either Micrometre or Nanometre Scale Surface Topography for Promoting Protein Adsorption and Cellular Response
Joint Authors
Fawcett, Derek
Berry, Cassandra M.
Le, Xuan Thi
Ali, Nurshahidah
Poinern, Gérrard Eddy Jai
Source
International Journal of Biomaterials
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-27
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Surface topographical features on biomaterials, both at the submicrometre and nanometre scales, are known to influence the physicochemical interactions between biological processes involving proteins and cells.
The nanometre-structured surface features tend to resemble the extracellular matrix, the natural environment in which cells live, communicate, and work together.
It is believed that by engineering a well-defined nanometre scale surface topography, it should be possible to induce appropriate surface signals that can be used to manipulate cell function in a similar manner to the extracellular matrix.
Therefore, there is a need to investigate, understand, and ultimately have the ability to produce tailor-made nanometre scale surface topographies with suitable surface chemistry to promote favourable biological interactions similar to those of the extracellular matrix.
Recent advances in nanoscience and nanotechnology have produced many new nanomaterials and numerous manufacturing techniques that have the potential to significantly improve several fields such as biological sensing, cell culture technology, surgical implants, and medical devices.
For these fields to progress, there is a definite need to develop a detailed understanding of the interaction between biological systems and fabricated surface structures at both the micrometre and nanometre scales.
American Psychological Association (APA)
Le, Xuan Thi& Poinern, Gérrard Eddy Jai& Ali, Nurshahidah& Berry, Cassandra M.& Fawcett, Derek. 2013. Engineering a Biocompatible Scaffold with Either Micrometre or Nanometre Scale Surface Topography for Promoting Protein Adsorption and Cellular Response. International Journal of Biomaterials،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-497632
Modern Language Association (MLA)
Le, Xuan Thi…[et al.]. Engineering a Biocompatible Scaffold with Either Micrometre or Nanometre Scale Surface Topography for Promoting Protein Adsorption and Cellular Response. International Journal of Biomaterials No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-497632
American Medical Association (AMA)
Le, Xuan Thi& Poinern, Gérrard Eddy Jai& Ali, Nurshahidah& Berry, Cassandra M.& Fawcett, Derek. Engineering a Biocompatible Scaffold with Either Micrometre or Nanometre Scale Surface Topography for Promoting Protein Adsorption and Cellular Response. International Journal of Biomaterials. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-497632
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497632