Hypotension, Syncope, and Fever in Systemic Mastocytosis without Skin Infiltration and Rapid Response to Corticosteroid and Cyclosporin : A Case Report
Joint Authors
Dagdelen, Selcuk
Agbaht, Kemal
Serefhanoglu, Songul
Erbas, Tomris
Ersoy-Evans, Sibel
Aksu, Salih
Ozdemir, Didem
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-20
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Mast cell disorders are defined by an abnormal accumulation of tissue mast cells in one or more organ systems.
In systemic mastocytosis, at least one extracutaneous organ is involved by definition.
Although, systemic mastocytosis usually represents with skin lesion called urticaria pigmentosa, in a small proportion, there is extracutaneous involvement without skin infiltration.
Other manifestations are flushing, tachycardia, dyspepsia, diarrhea, hypotension, syncope, and rarely fever.
Various medications have been used but there is not a definite cure for systemic mastocytosis.
The principles of treatment include control of symptoms with measures aimed to decrease mast cell activation.
We describe a case of systemic mastocytosis presenting with hypotension, syncope attacks, fever, and local flushing.
In bone marrow biopsy, increased mast cell infiltration was demonstrated.
She had no skin infiltration.
A good clinicopathological response was obtained acutely with combination therapy of glucocorticoid and cyclosporine.
American Psychological Association (APA)
Ozdemir, Didem& Dagdelen, Selcuk& Erbas, Tomris& Agbaht, Kemal& Serefhanoglu, Songul& Aksu, Salih…[et al.]. 2010. Hypotension, Syncope, and Fever in Systemic Mastocytosis without Skin Infiltration and Rapid Response to Corticosteroid and Cyclosporin : A Case Report. Case Reports in Medicine،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-497641
Modern Language Association (MLA)
Ozdemir, Didem…[et al.]. Hypotension, Syncope, and Fever in Systemic Mastocytosis without Skin Infiltration and Rapid Response to Corticosteroid and Cyclosporin : A Case Report. Case Reports in Medicine No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-497641
American Medical Association (AMA)
Ozdemir, Didem& Dagdelen, Selcuk& Erbas, Tomris& Agbaht, Kemal& Serefhanoglu, Songul& Aksu, Salih…[et al.]. Hypotension, Syncope, and Fever in Systemic Mastocytosis without Skin Infiltration and Rapid Response to Corticosteroid and Cyclosporin : A Case Report. Case Reports in Medicine. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-497641
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497641