Recombinant Protein Production of Earthworm Lumbrokinase for Potential Antithrombotic Application
Joint Authors
Tull, Lauren
Wang, Nan
Wang, Kevin Yueju
Liu, Dehu
Cooper, Edwin L.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Earthworms have been used as a traditional medicine in China, Japan, and other Far East countries for thousands of years.
Oral administration of dry earthworm powder is considered as a potent and effective supplement for supporting healthy blood circulation.
Lumbrokinases are a group of enzymes that were isolated and purified from different species of earthworms.
These enzymes are recognized as fibrinolytic agents that can be used to treat various conditions associated with thrombosis.
Many lumbrokinase (LK) genes have been cloned and characterized.
Advances in genetic technology have provided the ability to produce recombinant LK and have made it feasible to purify a single lumbrokinase enzyme for potential antithrombotic application.
In this review, we focus on expression systems that can be used for lumbrokinase production.
In particular, the advantages of using a transgenic plant system to produce edible lumbrokinase are described.
American Psychological Association (APA)
Wang, Kevin Yueju& Tull, Lauren& Cooper, Edwin L.& Wang, Nan& Liu, Dehu. 2013. Recombinant Protein Production of Earthworm Lumbrokinase for Potential Antithrombotic Application. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-497782
Modern Language Association (MLA)
Wang, Kevin Yueju…[et al.]. Recombinant Protein Production of Earthworm Lumbrokinase for Potential Antithrombotic Application. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-497782
American Medical Association (AMA)
Wang, Kevin Yueju& Tull, Lauren& Cooper, Edwin L.& Wang, Nan& Liu, Dehu. Recombinant Protein Production of Earthworm Lumbrokinase for Potential Antithrombotic Application. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-497782
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497782