A Survey of FDG- and Amyloid-PET Imaging in Dementia and GRADE Analysis
Joint Authors
Iaccarino, Leonardo
Carlo, Caltagirone
Perani, Daniela
Frisoni, Giovanni B.
Schillaci, Orazio
Padovani, Alessandro
Nobili, Flavio Mariano
Pasquale Anthony, Della Rosa
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-19
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Abstract EN
PET based tools can improve the early diagnosis of Alzheimer’s disease (AD) and differential diagnosis of dementia.
The importance of identifying individuals at risk of developing dementia among people with subjective cognitive complaints or mild cognitive impairment has clinical, social, and therapeutic implications.
Within the two major classes of AD biomarkers currently identified, that is, markers of pathology and neurodegeneration, amyloid- and FDG-PET imaging represent decisive tools for their measurement.
As a consequence, the PET tools have been recognized to be of crucial value in the recent guidelines for the early diagnosis of AD and other dementia conditions.
The references based recommendations, however, include large PET imaging literature based on visual methods that greatly reduces sensitivity and specificity and lacks a clear cut-off between normal and pathological findings.
PET imaging can be assessed using parametric or voxel-wise analyses by comparing the subject’s scan with a normative data set, significantly increasing the diagnostic accuracy.
This paper is a survey of the relevant literature on FDG and amyloid-PET imaging aimed at providing the value of quantification for the early and differential diagnosis of AD.
This allowed a meta-analysis and GRADE analysis revealing high values for PET imaging that might be useful in considering recommendations.Erratum to “A Survey of FDG- and Amyloid-PET Imaging in Dementia and GRADE Analysis”dx.doi.org/10.1155/2014/246586
American Psychological Association (APA)
Perani, Daniela& Schillaci, Orazio& Padovani, Alessandro& Nobili, Flavio Mariano& Iaccarino, Leonardo& Pasquale Anthony, Della Rosa…[et al.]. 2014. A Survey of FDG- and Amyloid-PET Imaging in Dementia and GRADE Analysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-22.
https://search.emarefa.net/detail/BIM-497880
Modern Language Association (MLA)
Perani, Daniela…[et al.]. A Survey of FDG- and Amyloid-PET Imaging in Dementia and GRADE Analysis. BioMed Research International No. 2014 (2014), pp.1-22.
https://search.emarefa.net/detail/BIM-497880
American Medical Association (AMA)
Perani, Daniela& Schillaci, Orazio& Padovani, Alessandro& Nobili, Flavio Mariano& Iaccarino, Leonardo& Pasquale Anthony, Della Rosa…[et al.]. A Survey of FDG- and Amyloid-PET Imaging in Dementia and GRADE Analysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-22.
https://search.emarefa.net/detail/BIM-497880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497880