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Preclinical and Clinical Effects of Mistletoe against Breast Cancer
Joint Authors
Marvibaigi, Mohsen
Jaganathan, Saravana Kumar
Abdul Majid, Fadzilah Adibah
Amini, Neda
Supriyanto, Eko
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-20
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Breast cancer is among the most frequent types of cancer in women worldwide.
Current conventional treatment options are accompanied by side effects.
Mistletoe is amongst the important herbal medicines traditionally used as complementary remedies.
An increasing number of studies have reported anticancer activity of mistletoe extracts on breast cancer cells and animal models.
Some recent evidence suggests that cytotoxic activity of mistletoe may be mediated through different mechanisms.
These findings provide a good base for clinical trials.
Various studies on mistletoe therapy for breast cancer patients revealed similar findings concerning possible benefits on survival time, health-related quality of life (HRQoL), remission rate, and alleviating adverse reactions to conventional therapy.
This review provides an overview of the recent findings on preclinical experiments and clinical trials of mistletoe for its cytotoxic and antitumor activity and its effect on HRQoL in breast cancer patients.
Moreover, studies investigating molecular and cellular mechanisms underlying antitumor activity of mistletoe are discussed in this paper.
The analyzed trials provided evidence that there might be a combination of pharmacological and motivational aspects mediated by the mistletoe extract application which may contribute to the clinical benefit and positive outcome such as improved HRQoL and self-regulation in breast cancer patients.
American Psychological Association (APA)
Marvibaigi, Mohsen& Supriyanto, Eko& Amini, Neda& Abdul Majid, Fadzilah Adibah& Jaganathan, Saravana Kumar. 2014. Preclinical and Clinical Effects of Mistletoe against Breast Cancer. BioMed Research International،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-497930
Modern Language Association (MLA)
Marvibaigi, Mohsen…[et al.]. Preclinical and Clinical Effects of Mistletoe against Breast Cancer. BioMed Research International No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-497930
American Medical Association (AMA)
Marvibaigi, Mohsen& Supriyanto, Eko& Amini, Neda& Abdul Majid, Fadzilah Adibah& Jaganathan, Saravana Kumar. Preclinical and Clinical Effects of Mistletoe against Breast Cancer. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-497930
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497930