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Higher Volume at Time of Breast Conserving Surgery Reduces Re-Excision in DCIS
Joint Authors
Shapiro, R.
Singh, B.
Cohen, J.
Wen, Y.
Axelrod, D.
Guth, Amber A.
Roses, D.
Wolf, J. H.
Source
International Journal of Surgical Oncology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-09
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
The purpose of this study was to compare the surgical and pathological variables which impact rate of re-excision following breast conserving therapy (BCS) with or without concurrent additional margin excision (AM).
Methods.
The pathology database was queried for all patients with DCIS from January 2004 to September 2008.
Pathologic assessment included volume of excision, subtype, size, distance from margin, grade, necrosis, multifocality, calcifications, and ER/PR status.
Results.
405 cases were identified and 201 underwent BCS, 151-BCS-AM, and 53-mastectomy.
Among the 201 BCS patients, 190 underwent re-excision for close or involved margins.
129 of these were treated with BCS and 61 with BCS-AM (P<.0001).
The incidence of residual DCIS in the re-excision specimens was 32% (n=65) for BCS and 22% (n=33) for BCS-AM (P<.05).
For both the BCS and the BCS-AM cohorts, volume of tissue excised is inversely correlated to the rate of re-excision (P=.0284).
Multifocality (P=.0002) and ER status (P=.0382) were also significant predictors for rate of re-excision and variation in surgical technique was insignificant.
Conclusions.
The rate of positive margins, re-excision, and residual disease was significantly higher in patients with lower volume of excision.
The performance of concurrent additional margin excision increases the efficacy of BCS for DCIS.
American Psychological Association (APA)
Wolf, J. H.& Wen, Y.& Axelrod, D.& Roses, D.& Guth, Amber A.& Shapiro, R.…[et al.]. 2011. Higher Volume at Time of Breast Conserving Surgery Reduces Re-Excision in DCIS. International Journal of Surgical Oncology،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-497955
Modern Language Association (MLA)
Wolf, J. H.…[et al.]. Higher Volume at Time of Breast Conserving Surgery Reduces Re-Excision in DCIS. International Journal of Surgical Oncology No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-497955
American Medical Association (AMA)
Wolf, J. H.& Wen, Y.& Axelrod, D.& Roses, D.& Guth, Amber A.& Shapiro, R.…[et al.]. Higher Volume at Time of Breast Conserving Surgery Reduces Re-Excision in DCIS. International Journal of Surgical Oncology. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-497955
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497955