Quantitative Estimation of the Nonstationary Behavior of Neural Spontaneous Activity
Joint Authors
Neves, Amanda F.
Moreira-Marques, Suelen
Murta-Junior, Luiz-Otavio
Destro-Filho, João-Batista
Chiappalone, Michela
Martinoia, Sergio
Estombelo-Montesco, Carlos-Alberto
Source
Computational Intelligence and Neuroscience
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-12-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The “stationarity time” (ST) of neuronal spontaneous activity signals of rat embryonic cortical cells, measured by means of a planar Multielectrode Array (MEA), was estimated based on the “Detrended Fluctuation Analysis” (DFA).
The ST is defined as the mean time interval during which the signal under analysis keeps its statistical characteristics constant.
An upgrade on the DFA method is proposed, leading to a more accurate procedure.
Strong statistical correlation between the ST, estimated from the Absolute Amplitude of Neural Spontaneous Activity (AANSA) signals and the Mean Interburst Interval (MIB), calculated by classical spike sorting methods applied to the interspike interval time series, was obtained.
In consequence, the MIB may be estimated by means of the ST, which further includes relevant biological information arising from basal activity.
The results point out that the average ST of MEA signals lies between 2-3 seconds.
Furthermore, it was shown that a neural culture presents signals that lead to different statistical behaviors, depending on the relative geometric position of each electrode and the cells.
Such behaviors may disclose physiological phenomena, which are possibly associated with different adaptation/facilitation mechanisms.
American Psychological Association (APA)
Destro-Filho, João-Batista& Estombelo-Montesco, Carlos-Alberto& Murta-Junior, Luiz-Otavio& Martinoia, Sergio& Chiappalone, Michela& Moreira-Marques, Suelen…[et al.]. 2009. Quantitative Estimation of the Nonstationary Behavior of Neural Spontaneous Activity. Computational Intelligence and Neuroscience،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-497965
Modern Language Association (MLA)
Destro-Filho, João-Batista…[et al.]. Quantitative Estimation of the Nonstationary Behavior of Neural Spontaneous Activity. Computational Intelligence and Neuroscience No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-497965
American Medical Association (AMA)
Destro-Filho, João-Batista& Estombelo-Montesco, Carlos-Alberto& Murta-Junior, Luiz-Otavio& Martinoia, Sergio& Chiappalone, Michela& Moreira-Marques, Suelen…[et al.]. Quantitative Estimation of the Nonstationary Behavior of Neural Spontaneous Activity. Computational Intelligence and Neuroscience. 2009. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-497965
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497965