Is Spectral-Domain Optical Coherence Tomography Essential for Flexible Treatment Regimens with Ranibizumab for Neovascular Age-Related Macular Degeneration?
Joint Authors
Ozkaya, Abdullah
Karakucuk, Yalcin
Alkin, Zeynep
Demirok, Ahmet
Ozgurhan, Engin Bilge
Yazici, Ahmet Taylan
Ozkaya, Hande Mefkure
Agca, Alper
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-11
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To evaluate the ability of spectral-domain optical coherence tomography to detect subtle amounts of retinal fluid when the choroidal neovascularization is detected as inactive via time-domain optical coherence tomography and clinical examination in neovascular age-related macular degeneration (nAMD) patients.
Methods.
Forty-nine eyes of 49 patients with nAMD after ranibizumab treatment were included in this cross-sectional, prospective study.
All patients were imaged with TD-OCT and SD-OCT at the same visit one month after a ranibizumab injection.
The presence of subretinal, intraretinal, and subretinal pigment epithelium fluid (subRPE) in SD-OCT was evaluated; also mean central retinal thickness (CRT) and the rate of vitreoretinal surface disorders detected via the two devices were evaluated.
Results.
The mean CRT via TD-OCT and SD-OCT was 218.1±51.3 and 325.7±78.8 microns.
Sixteen patients (32.6%) showed any kind of retinal fluid via SD-OCT.
In detail, 8 patients (16.3%) showed subretinal fluid, 10 patients (20.4%) showed intraretinal fluid, and 3 patients (6.1%) showed SubRPE fluid.
The ability of detecting vitreoretinal surface disorders was comparable between the two devices, except vitreomacular traction.
Conclusion.
SD-OCT is essential for the nAMD patients who are on an as-needed treatment regimen with ranibizumab.
Only TD-OCT and clinical examination may cause insufficient treatment in this group of patients.
American Psychological Association (APA)
Ozkaya, Abdullah& Alkin, Zeynep& Ozkaya, Hande Mefkure& Agca, Alper& Ozgurhan, Engin Bilge& Karakucuk, Yalcin…[et al.]. 2013. Is Spectral-Domain Optical Coherence Tomography Essential for Flexible Treatment Regimens with Ranibizumab for Neovascular Age-Related Macular Degeneration?. Journal of Ophthalmology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-497977
Modern Language Association (MLA)
Ozkaya, Abdullah…[et al.]. Is Spectral-Domain Optical Coherence Tomography Essential for Flexible Treatment Regimens with Ranibizumab for Neovascular Age-Related Macular Degeneration?. Journal of Ophthalmology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-497977
American Medical Association (AMA)
Ozkaya, Abdullah& Alkin, Zeynep& Ozkaya, Hande Mefkure& Agca, Alper& Ozgurhan, Engin Bilge& Karakucuk, Yalcin…[et al.]. Is Spectral-Domain Optical Coherence Tomography Essential for Flexible Treatment Regimens with Ranibizumab for Neovascular Age-Related Macular Degeneration?. Journal of Ophthalmology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-497977
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-497977