Evaluation of Mammary Cancer in 7,12-Dimethylbenz(a)anthracene-Induced Wister Rats by Asymmetrical Temperature Distribution Analysis Using Thermography : A Comparison with Serum CEA Levels and Histopathology
Joint Authors
Akila, R.
Sharath, D.
Raj, Baldev
Angeline Kirubha, S. P.
Venkataraman, B.
Anburajan, M.
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Animal surface temperature profile captured using infrared camera is helpful for the assessment of physiological responses associated with the regulation of body temperature.
Diagnosing breast cancer in early stage itself has a greater effect on the prognosis.
In this work, asymmetrical temperature distribution analysis of chemical carcinogen 7,12-dimethyl benz(a)anthracene-induced in the lower right flank region of Wistar rats (n=6) was carried out to test the potential of thermography in diagnosing mammary cancer and tumor growth over a period of nine weeks in comparison with histopathology results as standard.
Temperature difference between the tumor induced lower right and left side of flank region was significant (with P value <0.001), whereas in the abdomen and shoulder there was no significant difference in temperature between right and left sides.
Percentage of asymmetrical temperature difference in the tumor induced lower flank region was 0.5 to 2%, whereas in the other regions it was <0.5%.
Green pixel distribution in RGB color histogram was asymmetrical in the tumor induced lower flank region.
Temperature reduction was observed in the tumor induced region after the seventh day of carcinogen induction.
Asymmetrical thermogram analysis is the best method of diagnosing mammary cancer and for studying tumor development.
American Psychological Association (APA)
Angeline Kirubha, S. P.& Anburajan, M.& Venkataraman, B.& Akila, R.& Sharath, D.& Raj, Baldev. 2012. Evaluation of Mammary Cancer in 7,12-Dimethylbenz(a)anthracene-Induced Wister Rats by Asymmetrical Temperature Distribution Analysis Using Thermography : A Comparison with Serum CEA Levels and Histopathology. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-498007
Modern Language Association (MLA)
Angeline Kirubha, S. P.…[et al.]. Evaluation of Mammary Cancer in 7,12-Dimethylbenz(a)anthracene-Induced Wister Rats by Asymmetrical Temperature Distribution Analysis Using Thermography : A Comparison with Serum CEA Levels and Histopathology. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-498007
American Medical Association (AMA)
Angeline Kirubha, S. P.& Anburajan, M.& Venkataraman, B.& Akila, R.& Sharath, D.& Raj, Baldev. Evaluation of Mammary Cancer in 7,12-Dimethylbenz(a)anthracene-Induced Wister Rats by Asymmetrical Temperature Distribution Analysis Using Thermography : A Comparison with Serum CEA Levels and Histopathology. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-498007
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498007