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Androgens and Adipose Tissue in Males : A Complex and Reciprocal Interplay
Joint Authors
Fabbri, Andrea
Mammi, Caterina
Caprio, Massimiliano
Antelmi, Antonella
Cinti, Francesca
Calanchini, Matilde
Lenzi, Andrea
Rosano, Giuseppe M. C.
Source
International Journal of Endocrinology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Clinical evidence shows that in males obesity is frequently associated with hypogonadism and vice versa; also, low testosterone levels have been considered a “hallmark” of metabolic syndrome in men.
These observations indicate that there is a strict connection between anatomically and functionally distinct cell types such as white adipocytes and Leydig cells, that synthesize testosterone.
Adipose tissue is able to control several functions of the testis through its products secreted in the bloodstream.
On the other hand, circulating levels of testosterone and estradiol deeply affect adipocyte proliferation, differentiation, and fat mass distribution, hereby controlling critical metabolic functions, such as food intake, insulin sensitivity, vascular reactivity, and immunity.
This paper highlights the existing clinical and experimental evidence linking androgens and adipose tissue and illustrates the consequences occurring when the balance between fat mass distribution and eugonadism is lost.
American Psychological Association (APA)
Mammi, Caterina& Calanchini, Matilde& Antelmi, Antonella& Cinti, Francesca& Rosano, Giuseppe M. C.& Lenzi, Andrea…[et al.]. 2011. Androgens and Adipose Tissue in Males : A Complex and Reciprocal Interplay. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-498228
Modern Language Association (MLA)
Mammi, Caterina…[et al.]. Androgens and Adipose Tissue in Males : A Complex and Reciprocal Interplay. International Journal of Endocrinology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-498228
American Medical Association (AMA)
Mammi, Caterina& Calanchini, Matilde& Antelmi, Antonella& Cinti, Francesca& Rosano, Giuseppe M. C.& Lenzi, Andrea…[et al.]. Androgens and Adipose Tissue in Males : A Complex and Reciprocal Interplay. International Journal of Endocrinology. 2011. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-498228
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-498228